Object: Alzheimer's disease is a progressive, irreversible neurodegenerative disorder
associated with brain alterations. Diffusion tensor imaging (DTI) has contributed to identify …

Background Diffusion tensor imaging (DTI) is applied in investigation of brain biomarkers for
neurodevelopmental and neurodegenerative disorders. However, the quality of DTI …

Recently, the field of Alzheimer's disease (AD) research has adopted a new framework that
places the progression of AD along a continuum consisting of a preclinical stage, followed …

The integrity of the cholinergic system plays a central role in cognitive decline both in normal
aging and neurological disorders including Alzheimer's disease and vascular cognitive …

Mild cognitive impairment (MCI) during aging is often a harbinger of Alzheimer's disease,
and, therefore, early intervention to preserve cognitive abilities before the MCI symptoms …

The intervention at the stage of mild cognitive impairment (MCI) is promising for preventing
Alzheimer's disease (AD). This study aims to search for the optimal machine learning (ML) …

White matter (WM) degeneration is suggested to predict the early signs of Alzheimer's
disease (AD). The exact structural regions of brain circuitry involved are not known. This …

Background Approximately one third of recently diagnosed Parkinson's disease (PD)
patients experience cognitive decline. The nucleus basalis of Meynert (NBM) degenerates …

A key challenge in medical imaging is determining a precise correspondence between
image properties and tissue microstructure. This comparison is hindered by disparate scales …

It is well established that the cholesterol-transporter apolipoprotein ε (APOE) genotype is
associated with the risk of developing neurodegenerative diseases. Recently, brain …