Free radical damage in ischemia‐reperfusion injury: an obstacle in acute ischemic stroke after revascularization therapy

MS Sun, H Jin, X Sun, S Huang… - Oxidative medicine …, 2018 - Wiley Online Library
Acute ischemic stroke is a common cause of morbidity and mortality worldwide.
Thrombolysis with recombinant tissue plasminogen activator and endovascular …

The immunology of stroke: from mechanisms to translation

C Iadecola, J Anrather - Nature medicine, 2011 - nature.com
Immunity and inflammation are key elements of the pathobiology of stroke, a devastating
illness second only to cardiac ischemia as a cause of death worldwide. The immune system …

[HTML][HTML] Understanding acquired brain injury: a review

L Goldman, EM Siddiqui, A Khan, S Jahan… - Biomedicines, 2022 - mdpi.com
Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI).
In general, ABI does not result from congenital disorders, degenerative diseases, or by brain …

Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis

R Meng, K Asmaro, L Meng, Y Liu, C Ma, C Xi, G Li… - Neurology, 2012 - AAN Enterprises
Objective: This study aims to evaluate protective effects of brief repetitive bilateral arm
ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic …

Stroke research at a crossroad: asking the brain for directions

C Iadecola, J Anrather - Nature neuroscience, 2011 - nature.com
Ischemic stroke remains a vexing public health problem. Although progress has been made
in prevention and supportive care, efforts to protect the brain from ischemic cell death have …

Remote ischaemic conditioning—a new paradigm of self-protection in the brain

DC Hess, RA Blauenfeldt, G Andersen… - Nature Reviews …, 2015 - nature.com
Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …

Remote ischemic perconditioning as an adjunct therapy to thrombolysis in patients with acute ischemic stroke: a randomized trial

KD Hougaard, N Hjort, D Zeidler, L Sørensen… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Remote ischemic preconditioning is neuroprotective in models
of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to …

Chronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham …

C Hou, J Lan, Y Lin, H Song, Y Wang, W Zhao… - The Lancet …, 2022 - thelancet.com
Background Intracranial atherosclerotic stenosis (ICAS) is one of the most common causes
of stroke worldwide, and it is associated with a high risk of recurrent stroke with currently …

Neuroprotective effects and mechanisms of ischemic/hypoxic preconditioning on neurological diseases

J Liu, Y Gu, M Guo, X Ji - CNS neuroscience & therapeutics, 2021 - Wiley Online Library
As the organ with the highest demand for oxygen, the brain has a poor tolerance to ischemia
and hypoxia. Despite severe ischemia/hypoxia induces the occurrence and development of …

Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance

RA Stetler, RK Leak, Y Gan, P Li, F Zhang, X Hu… - Progress in …, 2014 - Elsevier
Preconditioning is a phenomenon in which brief episodes of a sublethal insult induce robust
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …