Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in the industrialized world. The prevalence of NAFLD is increasing, becoming a substantial …

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease spanning from simple
benign steatosis to steatohepatitis with fibrosis and scarring that can eventually lead to …

Background and objectives The therapeutic effects of the dopamine D2 receptor (D2R)
agonist, bromocriptine, in type 2 diabetes (T2D) have been attributed to central nervous …

Food intake, which is a highly reinforcing behavior, provides nutrients required for survival in
all animals. However, when fat and sugar consumption goes beyond the daily needs, it can …

Despite enormous global efforts within clinical research and medical practice to reduce
cardiovascular disease (s)(CVD), it still remains the leading cause of death worldwide. While …

Abstract Background: The dopamine (DA) D2 receptor (D2R) agonist bromocriptine (BC)
decreases body fat in animal and human models and increases lean muscle mass …

Obesity and its complications occur at alarming rates worldwide. Epidemiological data have
associated perinatal conditions, such as malnutrition, with the development of some …

Purpose To evaluate the dopaminergic signaling in human adipose tissue in the context of
obesity and type 2 diabetes (T2D) and potential direct implications in adipose tissue …

Background. Type 2 diabetes (T2DM) patients, including those in good glycemic control,
have an increased risk of cardiovascular disease (CVD). Maintaining good glycemic control …

An extended series of studies indicate that endogenous phase shifts in circadian neuronal
input signaling to the biological clock system centered within the hypothalamic …