Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease

W Britt - Human cytomegalovirus, 2008 - Springer
Infections with human cytomegalovirus (HCMV) are a major cause of morbidity and mortality
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …

New developments in the management of cytomegalovirus infection after solid organ transplantation

AJ Eid, RR Razonable - Drugs, 2010 - Springer
Despite remarkable advances in the diagnostic and therapeutic modalities for its
management, cytomegalovirus (CMV) remains one of the most important pathogens …

[HTML][HTML] Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients

D Kumar, S Chernenko, G Moussa, I Cobas… - American journal of …, 2009 - Elsevier
Late-onset cytomegalovirus (CMV) disease commonly occurs after discontinuation of
antiviral prophylaxis. We determined the utility of testing CD8+ T-cell response against CMV …

The CD4+ T cell response to human cytomegalovirus in healthy and immunocompromised people

EY Lim, SE Jackson, MR Wills - Frontiers in cellular and infection …, 2020 - frontiersin.org
While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …

[HTML][HTML] Cytomegalovirus infection after liver transplantation: current concepts and challenges

RR Razonable - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
Cytomegalovirus (CMV) is a common viral pathogen that influences the outcome of liver
transplantation. In addition to the direct effects of CMV syndrome and tissue-invasive …

State-of-the-art monitoring of cytomegalovirus-specific cell-mediated immunity after organ transplant: a primer for the clinician

A Egli, A Humar, D Kumar - Clinical infectious diseases, 2012 - academic.oup.com
Cytomegalovirus (CMV) is one of the most common infections after solid organ
transplantation. Improved assays to predict viral replication and disease would help refine …

[HTML][HTML] Pretransplant immediately early-1-specific T cell responses provide protection for CMV infection after kidney transplantation

O Bestard, M Lucia, E Crespo, B Van Liempt… - American Journal of …, 2013 - Elsevier
Cytomegalovirus (CMV) infection is still a major complication after kidney transplantation.
Although cytotoxic CMV-specific T cells play a crucial role controlling CMV survival and …

Impact of genetic polymorphisms in cytomegalovirus glycoprotein B on outcomes in solid-organ transplant recipients with cytomegalovirus disease

O Manuel, A Åsberg, X Pang, H Rollag… - Clinical infectious …, 2009 - academic.oup.com
Background. It is unknown whether specific viral polymorphisms affect in vivo therapeutic
response in patients with cytomegalovirus (CMV) disease. Polymorphisms in the CMV …

Clinical evaluation of safety and immunogenicity of PADRE-cytomegalovirus (CMV) and tetanus-CMV fusion peptide vaccines with or without PF03512676 adjuvant

C La Rosa, J Longmate, SF Lacey… - Journal of Infectious …, 2012 - academic.oup.com
Background. It has been reported that cytomegalovirus (CMV) pp65-specific T cells can
protect hematopoietic cell transplant (HCT) recipients from CMV complications. Two …

Preformed frequencies of cytomegalovirus (CMV)–specific memory T and B cells identify protected CMV-sensitized individuals among seronegative kidney transplant …

M Lúcia, E Crespo, E Melilli, JM Cruzado… - Clinical infectious …, 2014 - academic.oup.com
Background. Cytomegalovirus (CMV) infection remains a major complication after kidney
transplantation. Baseline CMV risk is typically determined by the serological presence of …