Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Pregnant women are susceptible to malaria during pregnancy. Plasmodium falciparum,
which sequesters in the placenta, causes the greatest disease, contributing significantly to …

The primary antigenic and virulence determinant of the human malaria parasite Plasmodium
falciparum is a variant surface protein called PfEMP1. Different forms of PfEMP1 are …

Plasmodium falciparum imposes an enormous burden upon the developing world, with 300
to 500 million cases and 1 to 2 million deaths per year (94). Despite extensive research …

Pregnancy-associated malaria (PAM) is a serious consequence of sequestration of
Plasmodium falciparum-parasitized erythrocytes (PE) in the placenta through adhesion to …

Malaria caused by Plasmodium species and transmitted by Anopheles mosquitoes affects
large human populations, while Ixodes ticks transmit Babesia species and cause …

Malaria parasites avoid immune clearance through their ability to systematically alter
antigens exposed on the surface of infected red blood cells. This is accomplished by tightly …

Malaria persists as an undiminished global problem, but the resources available to address
it have increased. Many tools for understanding its biology and epidemiology are well …

Apicomplexan parasites include many parasites of importance either for livestock or as
causative agents of human diseases. The importance of these parasites has been …

The pathogenesis of Plasmodium falciparum malaria is linked to the variant surface antigen
Pf EMP1, which mediates tethering of infected erythrocytes to the host endothelium and is …