Drug-tolerant persister cells in cancer: the cutting edges and future directions

Y Pu, L Li, H Peng, L Liu, D Heymann… - Nature Reviews …, 2023 - nature.com
Drug-tolerant persister (DTP) cell populations were originally discovered in antibiotic-
resistant bacterial biofilms. Similar populations with comparable features have since been …

[HTML][HTML] Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology

K Asleh, V Dery, C Taylor, M Davey… - Biomarker …, 2023 - Springer
While the field of precision oncology is rapidly expanding and more targeted options are
revolutionizing cancer treatment paradigms, therapeutic resistance particularly to …

FINDER: A Fluidly Confined CRISPR‐Based DNA Reporter on Living Cell Membranes for Rapid and Sensitive Cancer Cell Identification

Y Yin, W Xie, M Xiong, Y Gao, Q Liu… - Angewandte Chemie …, 2023 - Wiley Online Library
The accurate, rapid, and sensitive identification of cancer cells in complex physiological
environments is significant in biological studies, personalized medicine, and biomedical …

[HTML][HTML] Circulating tumor cells as liquid biopsy markers in cancer patients

DJ Smit, K Pantel - Molecular Aspects of Medicine, 2024 - Elsevier
Over the past decade, novel methods for enrichment and identification of cancer cells
circulating in the blood have been established. Blood-based detection of cancer cells and …

Beyond blood: Advancing the frontiers of liquid biopsy in oncology and personalized medicine

Y Bao, D Zhang, H Guo, W Ma - Cancer Science, 2024 - Wiley Online Library
Liquid biopsy is emerging as a pivotal tool in precision oncology, offering a noninvasive and
comprehensive approach to cancer diagnostics and management. By harnessing biofluids …

[HTML][HTML] miRNAs in pancreatic cancer progression and metastasis

ETY Mok, JL Chitty, TR Cox - Clinical & Experimental Metastasis, 2024 - Springer
Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells.
Dysregulation of miRNA expression and function has been linked to a variety of diseases …

Circulating tumor cells: from basic to translational research

LE Cortés-Hernández, Z Eslami-S, K Pantel… - Clinical …, 2024 - academic.oup.com
Background Metastasis is the leading cause of cancer-related deaths. Most studies have
focused on the primary tumor or on overt metastatic lesions, leaving a significant knowledge …

Employing nano-enabled artificial intelligence (AI)-based smart technologies for prediction, screening, and detection of cancer

V Chugh, A Basu, A Kaushik, S Bhansali, AK Basu - Nanoscale, 2024 - pubs.rsc.org
Cancer has been classified as a diverse illness with a wide range of subgroups. Its early
identification and prognosis, which have become a requirement of cancer research, are …

Unraveling the tumor microenvironment: insights into cancer metastasis and therapeutic strategies

M El-Tanani, SA Rabbani, R Babiker, I Rangraze… - Cancer Letters, 2024 - Elsevier
This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …

A Molecular Voyage: Multiomics Insights into Circulating Tumor Cells

YW Zhang, A Gvozdenovic, N Aceto - Cancer Discovery, 2024 - AACR
Circulating tumor cells (CTCs) play a pivotal role in metastasis, the leading cause of cancer-
associated death. Recent improvements of CTC isolation tools, coupled with a steady …