Global, regional, and national prevalence of HIV-1 drug resistance in treatment-naive and treatment-experienced children and adolescents: a systematic review and …

L Ge, Y Luo, X Li, Y Hu, L Sun, F Bu, D Shan… - eClinicalMedicine, 2024 - thelancet.com
Background Despite significant reductions in mother-to-child HIV-1 transmission risks due to
the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 …

Antiretrovirals to CCR5 CRISPR/Cas9 gene editing-A paradigm shift chasing an HIV cure

A Khan, N Paneerselvam, BR Lawson - Clinical Immunology, 2023 - Elsevier
The evolution of drug-resistant viral strains and anatomical and cellular reservoirs of HIV
pose significant clinical challenges to antiretroviral therapy. CCR5 is a coreceptor critical for …