HPV, hypoxia and radiation response in head and neck cancer

EL Göttgens, C Ostheimer, PN Span… - The British journal of …, 2018 - academic.oup.com
Over the last decades, the incidence of human papilloma virus (HPV) positive head and
neck squamous-cell carcinoma (HNSCC) has significantly increased. Infection with high-risk …

EGFR pathway targeting drugs in head and neck cancer in the era of immunotherapy

JJ Kang, A Ko, SH Kil, JMS Clair, DS Shin… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Receptor tyrosine kinases (RTKs) are cell surface receptors that bind growth factor ligands
and initiate cellular signaling. Of the 20 classes of RTKs, 7 classes, IV, VIII, and X, are linked …

The current burden of oropharyngeal cancer: a global assessment based on GLOBOCAN 2020

V Lorenzoni, AK Chaturvedi, J Vignat… - … Biomarkers & Prevention, 2022 - AACR
Background: Oropharyngeal cancer (OPC) is a complex disease whose etiologies, either
related to risk factors such as smoking or alcohol, or linked to HPV infection, are believed to …

[HTML][HTML] The current epidemic of HPV-associated oropharyngeal cancer: An 18-year Danish population-based study with 2,169 patients

M Zamani, C Grønhøj, DH Jensen, AF Carlander… - European Journal of …, 2020 - Elsevier
Background The objectives of this study were to investigate the incidence of high-risk
genotypes of human papillomavirus (HPV) in tumours of patients with oropharyngeal …

Vulvar cancer: two pathways with different localization and prognosis

F Hinten, A Molijn, L Eckhardt, L Massuger, W Quint… - Gynecologic …, 2018 - Elsevier
Background Two etiologic pathways for vulvar squamous cell carcinoma (SCC) are
described: in a background of lichen sclerosus and/or differentiated vulvar intraepithelial …

Human papillomavirus and the DNA damage response: exploiting host repair pathways for viral replication

CC Spriggs, LA Laimins - Viruses, 2017 - mdpi.com
High-risk human papillomaviruses (HPVs) are the causative agents of cervical and other
genital cancers. In addition, HPV infections are associated with the development of many …

PI3K/AKT/mTOR signaling pathway in HPV-driven head and neck carcinogenesis: therapeutic implications

F Aguayo, F Perez-Dominguez, JC Osorio, C Oliva… - Biology, 2023 - mdpi.com
Simple Summary A subgroup of cancers that arises in the zone of the head and neck
(HNCs) are caused by some types of human papillomavirus (HPV), so called high-risk (HR) …

Reprogramming of energy metabolism in response to radiotherapy in head and neck squamous cell carcinoma

A Cruz-Gregorio, I Martínez-Ramírez… - Cancers, 2019 - mdpi.com
Head and neck cancer (HNC) is the sixth cause of cancer-related death worldwide. Head
and neck squamous cells carcinoma (HNSCC) is the most frequent subtype of HNC. The …

Background paper for the recommendation of HPV vaccination for boys in Germany

A Takla, M Wiese-Posselt, T Harder… - Bundesgesundheitsblatt …, 2018 - Springer
Infections with human papillomaviruses (HPVs) are common among women and men [2].
HPV infections are thought to be among the most common sexually transmitted infections …

The role of cytokines in head and neck squamous cell carcinoma: A review

M Ralli, M Grasso, A Gilardi, M Ceccanti… - La Clinica …, 2020 - iris.uniroma1.it
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy
worldwide, accounting for approximately 6% of all cancer cases and responsible for an …