Background Many differences between different ethnic groups have been observed, such as
skin color, eye color, height, susceptibility to some diseases, and response to certain drugs …

Spondylo‐epi‐metaphyseal dysplasias with joint laxity, type 3 (SEMDJL3) is a genetic
skeletal disorder characterized by multiple joint dislocations, caused by biallelic pathogenic …

Positive natural selection can lead to a decrease in genomic diversity at the selected site
and at linked sites, producing a characteristic signature of elevated expected haplotype …

Most balanced translocations are thought to result mechanistically from nonhomologous end
joining or, in rare cases of recurrent events, by nonallelic homologous recombination. Here …

Dendrites lengthen by several orders of magnitude during neuronal development, but how
membrane is allocated in dendrites to facilitate this growth remains unclear. Here, we report …

Purpose The 2010 consensus statement on diagnostic chromosomal microarray (CMA)
testing recommended an array resolution≥ 400 kb throughout the genome as a balance of …

Positive selection causes beneficial alleles to rise to high frequency, resulting in a selective
sweep of the diversity surrounding the selected sites. Accordingly, the signature of a …

We report two brothers from a consanguineous couple with spondyloepimetaphyseal
dysplasia (SEMD), multiple joint dislocations at birth, severe joint laxity, scoliosis, gracile …

Cerebrovascular damage coexists with Alzheimer's disease (AD) pathology and increases
AD risk. However, it is unclear whether endothelial progenitor cells reduce AD risk via …

This study aimed to examine whether the relationship between mothers' DNA methylation
profiles and offspring's depression is modulated by negative parenting. The participants …