Satellite cells and the muscle stem cell niche
Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
Structure and function of the skeletal muscle extracellular matrix
AR Gillies, RL Lieber - Muscle & nerve, 2011 - Wiley Online Library
The skeletal muscle extracellular matrix (ECM) plays an important role in muscle fiber force
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …
Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
Ectopic fat deposition in skeletal muscle is closely associated with several disorders,
however, the origin of these adipocytes is not clear, nor is the mechanism of their formation …
however, the origin of these adipocytes is not clear, nor is the mechanism of their formation …
Role of pericytes in skeletal muscle regeneration and fat accumulation
A Birbrair, T Zhang, ZM Wang, ML Messi… - Stem cells and …, 2013 - liebertpub.com
Stem cells ensure tissue regeneration, while overgrowth of adipogenic cells may
compromise organ recovery and impair function. In myopathies and muscle atrophy …
compromise organ recovery and impair function. In myopathies and muscle atrophy …
Pericytes at the intersection between tissue regeneration and pathology
A Birbrair, T Zhang, ZM Wang, ML Messi… - Clinical …, 2015 - portlandpress.com
Perivascular multipotent cells, pericytes, contribute to the generation and repair of various
tissues in response to injury. They are heterogeneous in their morphology, distribution …
tissues in response to injury. They are heterogeneous in their morphology, distribution …
[HTML][HTML] Adipocyte lineages: tracing back the origins of fat
J Sanchez-Gurmaches, DA Guertin - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
The obesity epidemic has intensified efforts to understand the mechanisms controlling
adipose tissue development. Adipose tissue is generally classified as white adipose tissue …
adipose tissue development. Adipose tissue is generally classified as white adipose tissue …
[HTML][HTML] The effects of obesity on skeletal muscle regeneration
D Akhmedov, R Berdeaux - Frontiers in physiology, 2013 - frontiersin.org
Obesity and metabolic disorders such as type 2 diabetes mellitus are accompanied by
increased lipid deposition in adipose and non-adipose tissues including liver, pancreas …
increased lipid deposition in adipose and non-adipose tissues including liver, pancreas …
[HTML][HTML] Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla
Proton NMR spectroscopy at 7 Tesla (7T) was evaluated as a new method to quantify
human fat composition noninvasively. In validation experiments, the composition of a known …
human fat composition noninvasively. In validation experiments, the composition of a known …
[HTML][HTML] Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity
W Bakker, EC Eringa, P Sipkema… - Cell and tissue …, 2009 - Springer
Endothelial dysfunction comprises a number of functional alterations in the vascular
endothelium that are associated with diabetes and cardiovascular disease, including …
endothelium that are associated with diabetes and cardiovascular disease, including …
[HTML][HTML] Reduced physical activity increases intermuscular adipose tissue in healthy young adults
Background: Recent findings suggest that higher levels of intermuscular adipose tissue
(IMAT) are associated with glucose dysregulation, lower levels of muscle strength, and a …
(IMAT) are associated with glucose dysregulation, lower levels of muscle strength, and a …