GPR55 is a class A orphan G protein-coupled receptor that has drawn important therapeutic
attention in the last decade because of its role in pathophysiological processes including …

The use of cannabis preparations has steadily increased. Although cannabis was
traditionally assumed to only have mild vegetative side effects, it has become evident in …

Up to 20% of pregnant women ages 18–24 consume cannabis during pregnancy. Moreover,
clinical studies indicate that cannabis consumption during pregnancy leads to fetal growth …

Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that
target the endocannabinoid system in many body organs. SCs can initiate …

Cardiovascular disease (CVD) causes millions of deaths worldwide each year. Despite the
great progress in therapies available for patients with CVD, some limitations, including drug …

Dissecting the pathways regulating the adaptive immune response in atherosclerosis is of
particular therapeutic interest. Here we report that the lipid G-protein-coupled receptor …

Ischemic heart disease, associated with high morbidity and mortality, represents a major
challenge for the development of drug-based strategies to improve its prognosis. Results of …

Background Cannabis is one of the most widely used psychoactive substances. Its
components act through several pathways, producing a myriad of side effects, of which …

The tumor microenvironment (TME) is a dynamic environment that surrounds tumors,
composed of infiltrated/resident host cells, the extracellular matrix (ECM), and soluble …

Arg1 Murine arginase 1 gene ATF-2 Activating transcription factor 2 BAFF B-cell activating
factor BCR B-cell receptor BKCa Large-conductance Ca2+-and voltage-gated big K+ …