Porcine cells devoid of three major carbohydrate xenoantigens, αGal, Neu5GC, and SDa
(TKO) exhibit markedly reduced binding of human natural antibodies. Therefore, it is …

Survival of pig cardiac xenografts in a non-human primate (NHP) model has improved
significantly over the last 4 years with the introduction of costimulation blockade-based …

Xenogeneic transplantation and tolerance in the era of CRISP... : Current Opinion in Organ
Transplantation Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9 …

Abstract Purpose of Review With the exponential increase in interest and great strides
toward clinical application, many experts believe we are ready for kidney xenotransplant …

Simple Summary Short repeated sequences of DNA at the end of chromosomes are called
telomeres; these help to maintain the chromosome structure. During normal cell replication …

Most importantly, these numbers only reflect the patients who were listed for transplantation.
Many patients are too sick to be added to the list. There are also patients with hepatocellular …

Pigs provide valuable meat sources, disease models, and research materials for humans.
However, traditional methods no longer meet the developing needs of pig production. More …

To study the pathophysiology of human diseases, develop innovative treatments, and refine
approaches for regenerative medicine require appropriate preclinical models. Pigs share …

O xenotransplante (xenoTx), ou transplante interespécie, é definido como o transplante de
órgãos, tecidos ou células entre diferentes espécies e representa uma das propostas mais …

Xenotransplantation is defined as the transplantation of organs, tissues, and cells between
organisms of different species. The use of organs from these animals would theoretically …