Kidney transplantation from triple‐knockout pigs expressing multiple human proteins in cynomolgus macaques
D Ma, T Hirose, G Lassiter, H Sasaki… - American Journal of …, 2022 - Wiley Online Library
Porcine cells devoid of three major carbohydrate xenoantigens, αGal, Neu5GC, and SDa
(TKO) exhibit markedly reduced binding of human natural antibodies. Therefore, it is …
(TKO) exhibit markedly reduced binding of human natural antibodies. Therefore, it is …
[HTML][HTML] Cardiac xenotransplantation: progress in preclinical models and prospects for clinical translation
AK Singh, CE Goerlich, AM Shah… - Transplant …, 2022 - frontierspartnerships.org
Survival of pig cardiac xenografts in a non-human primate (NHP) model has improved
significantly over the last 4 years with the introduction of costimulation blockade-based …
significantly over the last 4 years with the introduction of costimulation blockade-based …
Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9
PJ Cowan, WJ Hawthorne… - Current Opinion in Organ …, 2019 - journals.lww.com
Xenogeneic transplantation and tolerance in the era of CRISP... : Current Opinion in Organ
Transplantation Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9 …
Transplantation Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9 …
[HTML][HTML] Kidney Xenotransplantation: Are We Ready for Prime Time?
RMN Dos Santos - Current Urology Reports, 2023 - Springer
Abstract Purpose of Review With the exponential increase in interest and great strides
toward clinical application, many experts believe we are ready for kidney xenotransplant …
toward clinical application, many experts believe we are ready for kidney xenotransplant …
[HTML][HTML] Telomere dynamics in livestock
N Zhang, EC Baker, TH Welsh Jr, DG Riley - Biology, 2023 - mdpi.com
Simple Summary Short repeated sequences of DNA at the end of chromosomes are called
telomeres; these help to maintain the chromosome structure. During normal cell replication …
telomeres; these help to maintain the chromosome structure. During normal cell replication …
[HTML][HTML] Insights into pig liver xenotransplantation
RMN Dos Santos - Gastroenterology & Hepatology, 2022 - ncbi.nlm.nih.gov
Most importantly, these numbers only reflect the patients who were listed for transplantation.
Many patients are too sick to be added to the list. There are also patients with hepatocellular …
Many patients are too sick to be added to the list. There are also patients with hepatocellular …
Application and development of CRISPR/cas9 technology in pig research
H Lin, Q Deng, L Li, L Shi - Gene Editing-Technologies and …, 2019 - books.google.com
Pigs provide valuable meat sources, disease models, and research materials for humans.
However, traditional methods no longer meet the developing needs of pig production. More …
However, traditional methods no longer meet the developing needs of pig production. More …
[HTML][HTML] Targeted gene editing in porcine spermatogonia
D Webster, A Bondareva, S Solin, T Goldsmith… - Frontiers in …, 2021 - frontiersin.org
To study the pathophysiology of human diseases, develop innovative treatments, and refine
approaches for regenerative medicine require appropriate preclinical models. Pigs share …
approaches for regenerative medicine require appropriate preclinical models. Pigs share …
Xenotransplante
FHF Galvao, LAC D'Albuquerque - Revista de Medicina, 2020 - revistas.usp.br
O xenotransplante (xenoTx), ou transplante interespécie, é definido como o transplante de
órgãos, tecidos ou células entre diferentes espécies e representa uma das propostas mais …
órgãos, tecidos ou células entre diferentes espécies e representa uma das propostas mais …
[HTML][HTML] Bioethics and xenotransplantation from pig to human
FHF Galvao, M Grinberg - Clinics, 2023 - SciELO Brasil
Xenotransplantation is defined as the transplantation of organs, tissues, and cells between
organisms of different species. The use of organs from these animals would theoretically …
organisms of different species. The use of organs from these animals would theoretically …