The rapid progress in the field of stem cell research has laid strong foundations for their use
in regenerative medicine applications of injured or diseased tissues. Growing evidences …

Muscular dystrophies are a group of genetic muscle disorders that cause progressive
muscle weakness and degeneration. Within this group, Duchenne muscular dystrophy …

Dystrophin proteomic regulation in muscular dystrophies (MDs) remains unclear. We report
that a long noncoding RNA (lncRNA), H19, associates with dystrophin and inhibits E3-ligase …

Skeletal muscle is an ideal target for cell therapy. The use of its potent stem cell population
in the form of autologous intramuscular transplantation represents a tantalizing strategy to …

Satellite cells (SC) are muscle stem cells that can regenerate adult muscles upon injury.
Most SC originate from PAX7+ myogenic precursors set aside during development …

Cultured meat production has emerged as a breakthrough technology for the global food
industry with the potential to reduce challenges associated with environmental sustainability …

Embryonic stem cells (ESCs) can adopt lineage-specific gene-expression programs by
stepwise exposure to defined factors, resulting in the generation of functional cell types. Bulk …

The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy
is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic …

The transplantation of muscle progenitor cells (MuPCs) differentiated from human induced
pluripotent stem cells (hiPSCs) is a promising approach for treating skeletal muscle …

Duchenne muscular dystrophy (DMD) is a lethal, X-linked neuromuscular disorder caused
by the absence of dystrophin protein, which is essential for muscle fiber integrity. Loss of …