COPD and multimorbidity: recognising and addressing a syndemic occurrence

LM Fabbri, BR Celli, A Agustí, GJ Criner… - The Lancet …, 2023 - thelancet.com
Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …

Treatable traits in airway disease: from theory to practice

A Agusti, PG Gibson, VM McDonald - The Journal of Allergy and Clinical …, 2023 - Elsevier
Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are
prevalent and complex conditions that often coexist in the same patient. To address this …

From treatable traits to GETomics in airway disease: moving towards clinical practice

A Papi, R Faner, I Pavord, F Baraldi… - European …, 2024 - Eur Respiratory Soc
The treatable traits approach represents a strategy for patient management. It is based on
the identification of characteristics susceptible to treatments or predictive of treatment …

Rational use of inhaled corticosteroids for the treatment of COPD

JK Quint, A Ariel, PJ Barnes - npj Primary Care Respiratory Medicine, 2023 - nature.com
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …

Multidisciplinary care in chronic airway diseases: the Newcastle model

VM McDonald, J Harrington, VL Clark… - ERJ Open …, 2022 - Eur Respiratory Soc
Chronic airway diseases including asthma and COPD are prevalent and high-burden
conditions with the majority of patients successfully managed in the primary care setting …

COPD‐X Australian guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2022 update

E Dabscheck, J George, K Hermann… - Medical Journal of …, 2022 - Wiley Online Library
Introduction Chronic obstructive pulmonary disease (COPD) is a treatable and preventable
disease characterised by persistent respiratory symptoms and chronic airflow limitation on …

Treatable traits models of care

VM McDonald, AE Holland - Respirology, 2024 - Wiley Online Library
Treatable traits is a personalized approach to the management of respiratory disease. The
approach involves a multidimensional assessment to understand the traits present in …

Unravelling the complex interplay of factors behind exercise limitations and physical inactivity in COPD

CY Tang, B Bernstein, F Blackstock, A Blondeel… - Breathe, 2024 - Eur Respiratory Soc
Exercise limitation and physical inactivity are known treatable traits for people with COPD.
Maximising exercise capacity and keeping people physically active improves health status …

An update on outcomes for COPD pharmacological trials: a COPD investigators report-reassessment of the 2008 American Thoracic Society/European Respiratory …

M Cazzola, P Rogliani, PJ Barnes, F Blasi… - American Journal of …, 2023 - atsjournals.org
Background: In 2008, a dedicated American Thoracic Society/European Respiratory Society
task force published a paper on the possible use and limitations of clinical outcomes and …

Inhibition of oxidative stress by apocynin attenuated chronic obstructive pulmonary disease progression and vascular injury by cigarette smoke exposure

SMH Chan, K Brassington… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Cardiovascular disease affects up to half of the patients with
chronic obstructive pulmonary disease (COPD), exerting deleterious impact on health …