[WITHDRAWN] retinal vasculature in development and diseases

Y Sun, LEH Smith - Annual review of vision science, 2018 - annualreviews.org
This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …

Suppressors of cytokine signaling: potential immune checkpoint molecules for cancer immunotherapy

S Chikuma, M Kanamori, S Mise‐Omata… - Cancer …, 2017 - Wiley Online Library
Inhibition of immune checkpoint molecules, PD‐1 and CTLA 4, has been shown to be a
promising cancer treatment. PD‐1 and CTLA 4 inhibit TCR and co‐stimulatory signals. The …

[HTML][HTML] m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2 …

R Wu, Y Liu, Y Zhao, Z Bi, Y Yao, Q Liu, F Wang… - Cell death & …, 2019 - nature.com
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold great promise
for regenerative medicine, disease treatment, and organ transplantation. As the ethical issue …

Sirt1: a guardian of the development of diabetic retinopathy

M Mishra, AJ Duraisamy, RA Kowluru - Diabetes, 2018 - Am Diabetes Assoc
Diabetic retinopathy is a multifactorial disease, and the exact mechanism of its pathogenesis
remains obscure. Sirtuin 1 (Sirt1), a multifunctional deacetylase, is implicated in the …

[HTML][HTML] Retinopathy of prematurity: Metabolic risk factors

Z Fu, AK Nilsson, A Hellstrom, LEH Smith - Elife, 2022 - elifesciences.org
At preterm birth, the retina is incompletely vascularized. Retinopathy of prematurity (ROP) is
initiated by the postnatal suppression of physiological retinal vascular development that …

Melatonin attenuated retinal neovascularization and neuroglial dysfunction by inhibition of HIF‐1α‐VEGF pathway in oxygen‐induced retinopathy mice

Y Xu, X Lu, Y Hu, B Yang, CK Tsui, S Yu… - Journal of pineal …, 2018 - Wiley Online Library
Retinopathy of prematurity (ROP) is a retinopathy characterized by retinal
neovascularization (RNV) occurring in preterm infants treated with high concentrations of …

Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos

Y Sun, Z Lin, CH Liu, Y Gong, R Liegl… - Journal of Experimental …, 2017 - rupress.org
Pathological neovessels growing into the normally avascular photoreceptors cause vision
loss in many eye diseases, such as age-related macular degeneration and macular …

Silencing microRNA‐221/222 cluster suppresses glioblastoma angiogenesis by suppressor of cytokine signaling‐3‐dependent JAK/STAT pathway

CH Xu, Y Liu, LM Xiao, LK Chen… - Journal of Cellular …, 2019 - Wiley Online Library
Angiogenesis is a major pathologic characteristic of glioblastoma, which is one aggressive
primary brain tumor. MicroRNA‐221/222 (miR‐221/222) cluster has been previously …

[HTML][HTML] MicroRNAs in hyperglycemia induced endothelial cell dysfunction

M Silambarasan, JR Tan, DS Karolina… - International Journal of …, 2016 - mdpi.com
Hyperglycemia is closely associated with prediabetes and Type 2 Diabetes Mellitus.
Hyperglycemia increases the risk of vascular complications such as diabetic retinopathy …

[HTML][HTML] Ocular vascular diseases: from retinal immune privilege to inflammation

X Wang, T Wang, E Lam, D Alvarez, Y Sun - International Journal of …, 2023 - mdpi.com
The eye is an immune privileged tissue that insulates the visual system from local and
systemic immune provocation to preserve homeostatic functions of highly specialized retinal …