DNA methylation as a diagnostic, prognostic, and predictive biomarker in head and neck cancer

G Liouta, M Adamaki, A Tsintarakis… - International Journal of …, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is a term collectively used to describe
all cancers that develop in the oral and nasal cavities, the paranasal sinuses, the salivary …

It takes two to tango: a review of oncogenic virus and host microbiome associated Inflammation in head and neck cancer

MG McKeon, JN Gallant, YJ Kim, SR Das - Cancers, 2022 - mdpi.com
Simple Summary Certain viruses, specifically, human papillomavirus (HPV) and Epstein–
Barr virus (EBV), have been linked with the development of head and neck cancer. In this …

Oral Papillomatosis: Its Relation with Human Papilloma Virus Infection and Local Immunity—An Update

EC Andrei, IM Baniță, MC Munteanu, CJ Busuioc… - Medicina, 2022 - mdpi.com
Oral papilloma lesions may appear as a result of HPV infection, or not, and only special
molecular methods could differentiate them. Low-risk and high-risk HPV types could induce …

Current and Emerging Diagnostic, Prognostic, and Predictive Biomarkers in Head and Neck Cancer

HW Eberly, BY Sciscent, FJ Lorenz, EM Rettig, N Goyal - Biomedicines, 2024 - mdpi.com
Head and neck cancers (HNC) are a biologically diverse set of cancers that are responsible
for over 660,000 new diagnoses each year. Current therapies for HNC require a …

Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers

M Inchanalkar, S Srivatsa, S Ambatipudi, PG Bhosale… - Clinical …, 2023 - Springer
Background Gingivobuccal complex oral squamous cell carcinoma (GBC-OSCC) is an
aggressive malignancy with high mortality often preceded by premalignant lesions …

Role of Histone Deacetylases in the Pathogenesis of Salivary Gland Tumors and Therapeutic Targeting Options

M Manou, DS Kanakoglou, T Loupis… - International Journal of …, 2023 - mdpi.com
Salivary gland tumors (SGTs) comprise a rare and heterogenous category of
benign/malignant neoplasms with progressively increasing knowledge of the molecular …

Tracking the molecular fingerprint of head and neck cancer for recurrence detection in liquid biopsies

A Diez-Fraile, J De Ceulaer, C Derpoorter… - International Journal of …, 2022 - mdpi.com
The 5-year relative survival for patients with head and neck cancer, the seventh most
common form of cancer worldwide, was reported as 67% in developed countries in the …

Somatostatin receptor2 (SSTR2) expression, prognostic implications, modifications and potential therapeutic strategies associates with head and neck squamous cell …

S Fan, H Zheng, Y Xu, Y Zhan, J Luo, H Zang… - Critical Reviews in …, 2023 - Elsevier
Head and neck squamous cell carcinomas (HNSCC) constitute a heterogeneous cluster of
tumors celebrated for their predisposition to metastasize and exhibit local recurrence …

SP1 Gene Methylation in Head and Neck Squamous Cell Cancer in HPV-Negative Patients

E Jumaniyazova, A Aghajanyan, S Kurevlev… - Genes, 2024 - mdpi.com
There is still much to learn about the epigenetic mechanisms controlling gene expression
during carcinogenesis. When researching aberrant DNA methylation, active proliferative …

The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer

A Kršek, L Batičić, T Braut, V Sotošek - Biomolecules, 2024 - unirepository.svkri.uniri.hr
Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma
(HNSCC), particularly oropharyngeal squamous cell carcinoma (OPSCC), is an increasingly …