Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Plant growth-promoting bacteria (PGPB) with biofilm-forming ability: a multifaceted agent for sustainable agriculture

N Ajijah, A Fiodor, AK Pandey, A Rana, K Pranaw - Diversity, 2023 - mdpi.com
Plant growth-promoting bacteria (PGPB) enhance plant growth, as well as protect plants
from several biotic and abiotic stresses through a variety of mechanisms. Therefore, the …

Engineering extracellular electron transfer pathways of electroactive microorganisms by synthetic biology for energy and chemicals production

J Zhang, F Li, D Liu, Q Liu, H Song - Chemical Society Reviews, 2024 - pubs.rsc.org
The excessive consumption of fossil fuels causes massive emission of CO2, leading to
climate deterioration and environmental pollution. The development of substitutes and …

[HTML][HTML] Polymicrobial infections and biofilms: clinical significance and eradication strategies

VT Anju, S Busi, M Imchen, R Kumavath, MS Mohan… - Antibiotics, 2022 - mdpi.com
Biofilms are population of cells growing in a coordinated manner and exhibiting resistance
towards hostile environments. The infections associated with biofilms are difficult to control …

The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine

F Le Mauff, E Razvi, C Reichhardt, P Sivarajah… - Communications …, 2022 - nature.com
The genetic capacity to synthesize the biofilm matrix exopolysaccharide Pel is widespread
among Gram-negative and Gram-positive bacteria. However, its exact chemical structure …

Natural and synthetic molecules with potential to enhance biofilm formation and virulence properties in Pseudomonas aeruginosa

GJ Jeong, F Khan, N Tabassum… - Critical Reviews in …, 2023 - Taylor & Francis
Pseudomonas aeruginosa can efficiently adapt to changing environmental conditions due to
its ubiquitous nature, intrinsic/acquired/adaptive resistance mechanisms, high metabolic …

Relationship between Biofilm-Formation, Phenotypic Virulence Factors and Antibiotic Resistance in Environmental Pseudomonas aeruginosa

P Behzadi, M Gajdács, P Pallós, B Ónodi, A Stájer… - Pathogens, 2022 - mdpi.com
The formation of a protective biofilm by Pseudomonas aeruginosa (PA) is one of the
hallmarks of their survival both in vivo and in harsh environmental conditions, thus, biofilm …

A review of chemical signaling pathways in the quorum sensing circuit of Pseudomonas aeruginosa

K Vadakkan, AK Ngangbam, K Sathishkumar… - International Journal of …, 2023 - Elsevier
Pseudomonas aeruginosa, an increasingly common competitive and biofilm organism in
healthcare infection with sophisticated, interlinked and hierarchic quorum systems (Las, Rhl …

Enterococcus faecalis antagonizes Pseudomonas aeruginosa growth in mixed-species interactions

CAZ Tan, LN Lam, G Biukovic, EYC Soh… - Journal of …, 2022 - Am Soc Microbiol
Enterococcus faecalis is often coisolated with Pseudomonas aeruginosa in polymicrobial
biofilm-associated infections of wounds and the urinary tract. As a defense strategy, the host …