Major depressive disorder as a neuro-immune disorder: origin, mechanisms, and therapeutic opportunities

GZ Réus, LM Manosso, J Quevedo… - … & Biobehavioral Reviews, 2023 - Elsevier
Notwithstanding advances in understanding the pathophysiology of major depressive
disorder (MDD), no single mechanism can explain all facets of this disorder. An expanding …

Vitamin B12: Strategies for enhanced production, fortified functional food products and health benefits

R Kumar, U Singh, A Tiwari, P Tiwari, JK Sahu… - Process …, 2023 - Elsevier
Vitamin B 12 is an essential micronutrient that controls many biological functions such as the
production of red blood cells (RBCs), DNA synthesis, functioning of nervous system and …

[HTML][HTML] Correlation of systemic immune-inflammation index and moderate/major depression in patients with depressive disorders: a large sample cross-sectional …

S Cui, J Li, Y Liu, G Yao, Y Wu, Z Liu, L Sun… - Frontiers in …, 2023 - frontiersin.org
Objective To evaluate the clinical value of systemic immune-inflammation index (SII) based
on peripheral blood neutrophil, lymphocyte, and platelet count in evaluating the subtype and …

[HTML][HTML] Residual symptoms and their associated factors among Thai patients with depression: a multihospital-based survey

J Pitanupong, K Sathaporn, L Tepsuan - Annals of General Psychiatry, 2022 - Springer
Background Depression is a common and debilitating disease, and even residual symptoms
of depression can cause significant functional impairment. To achieve normal functioning …

Urine Metabolite Analysis to Identify Pathomechanisms of Long COVID: A Pilot Study

M Taenzer, J Löffler-Ragg, A Schroll… - International …, 2023 - journals.sagepub.com
Background: Around 10% of people who had COVID-9 infection suffer from persistent
symptoms such as fatigue, dyspnoea, chest pain, arthralgia/myalgia, sleep disturbances …

Peripheral inflammation associated with depression and reduced weight loss: a longitudinal study of bariatric patients

AP McLaughlin, E Lambert, R Milton… - Psychological …, 2024 - cambridge.org
BackgroundResearch implicates inflammation in the vicious cycle between depression and
obesity, yet few longitudinal studies exist. The rapid weight loss induced by bariatric surgery …

Total saponins of panax ginseng via the CX3CL1/CX3CR1 axis attenuates neuroinflammation and exerted antidepressant‐like effects in chronic unpredictable mild …

M Qin, C Chen, N Wang, D Yu, S Yu… - Phytotherapy …, 2023 - Wiley Online Library
Total saponins of Panax ginseng (TSPG) have antidepressant effects. However, the
underlying antidepressant mechanism of TSPG remains not clear. This study aimed to …

Depression and HIV: a scoping review in search of neuroimmune biomarkers

A Mudra Rakshasa-Loots - Brain Communications, 2023 - academic.oup.com
People with HIV are at increased risk for depression, though the neurobiological
mechanisms underlying this are unclear. In the last decade, there has been a substantial …

[HTML][HTML] Blood concentrations of anterior pituitary hormones in drug-naive people with first-episode psychosis: A systematic review and meta-analysis

D Cavaleri, CA Capogrosso, P Guzzi… - …, 2023 - Elsevier
Introduction The role of anterior pituitary hormones–ie, adrenocorticotropic hormone
(ACTH), luteinizing and follicle stimulating hormones (LH and FSH), growth hormone (GH) …

[HTML][HTML] Evaluation of neopterin levels and kynurenine pathway in patients with acute coronary syndrome

I Kember, S Sanajou, B Kilicarslan, G Girgin… - Acute and Critical …, 2023 - ncbi.nlm.nih.gov
Background Coronary atherosclerosis is the leading cause of coronary artery disease.
Several investigations have indicated that tear-sensitive plaques contain macrophages and …