Hepatic malignancies remain a global challenge. Hepatocellular carcinoma (HCC) accounts
for around 90% of patients with liver cancer and is the sixth most common neoplasm …

The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …

Glioblastoma multiform (GBM) is considered as the most lethal tumor among CNS
malignancies. Although immunotherapy has achieved remarkable advances in cancer …

Pro-inflammatory cytokines can effectively be used for tumor immunotherapy, affecting every
step of the tumor immunity cycle. Thereby, they can restore antigen priming, improve the …

Non-coding RNAs (ncRNAs) are a group of molecules critical for cell development and
growth regulation. They are key regulators of important cellular pathways in the tumor …

The accumulation of mutations in cancer driver genes, such as tumor suppressors or
protooncogenes, affects cellular homeostasis. Disturbances in the mechanism controlling …

Although type I interferons (IFNs) play multifaceted roles during tumorigenesis and cancer
treatment, the interplay between type I IFNs and estrogen signaling in breast cancer (BC) …

Interferon-β (IFN-β) is a pleiotropic cytokine used for therapy of multiple sclerosis, which is
also effective in suppression of viral and bacterial infections and cancer. Recently, we …

The MHC-I antigen presentation (AP) pathway is key to shaping mammalian CD8+ T cell
immunity, with its aberrant expression closely linked to low tumor immunogenicity and …

The current understanding of the effects of radiation is gradually becoming broader.
However, it still remains unclear why some patients respond to radiation with a pronounced …