Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

GC Ulett, M Totsika, K Schaale, AJ Carey… - Current opinion in …, 2013 - Elsevier
Urinary tract infections (UTI) are among the most common infectious diseases of humans
and are the most common nosocomial infections in the developed world. It is estimated that …

[HTML][HTML] Alternative therapeutic options to antibiotics for the treatment of urinary tract infections

P Loubet, J Ranfaing, A Dinh… - Frontiers in …, 2020 - frontiersin.org
Urinary tract infections (UTIs) mainly caused by Uropathogenic Escherichia coli (UPEC), are
common bacterial infections. Many individuals suffer from chronically recurring UTIs …

Roles of eicosanoids in regulating inflammation and neutrophil migration as an innate host response to bacterial infections

AEF Sheppe, MJ Edelmann - Infection and Immunity, 2021 - Am Soc Microbiol
Eicosanoids are lipid-based signaling molecules that play a unique role in innate immune
responses. The multiple types of eicosanoids, such as prostaglandins (PGs) and …

[HTML][HTML] Inhibition of cyclooxygenase-2 prevents chronic and recurrent cystitis

TJ Hannan, PL Roberts, TE Riehl, S van der Post… - …, 2014 - thelancet.com
The spread of multidrug-resistant microorganisms globally has created an urgent need for
novel therapeutic strategies to combat urinary tract infections (UTIs). Immunomodulatory …

Strengths and limitations of model systems for the study of urinary tract infections and related pathologies

AE Barber, JP Norton, TJ Wiles… - … and Molecular Biology …, 2016 - Am Soc Microbiol
Urinary tract infections (UTIs) are some of the most common bacterial infections worldwide
and are a source of substantial morbidity among otherwise healthy women. UTIs can be …

[HTML][HTML] Intracellular colon cancer-associated Escherichia coli promote protumoral activities of human macrophages by inducing sustained COX-2 expression

J Raisch, N Rolhion, A Dubois… - Laboratory …, 2015 - Elsevier
Intestinal dysbiosis has been reported in patients with colorectal cancer, and there is a high
prevalence of Escherichia coli belonging to B2 phylogroup and producing a genotoxin …

[HTML][HTML] Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder …

I Demirel, A Persson, A Brauner, E Särndahl… - Frontiers in cellular …, 2018 - frontiersin.org
The NLRP3 inflammasome and IL-1β release have recently been suggested to be important
for the progression of urinary tract infection (UTI). However, much is still unknown regarding …

[HTML][HTML] The immune responses to different Uropathogens call individual interventions for bladder infection

L Li, Y Li, J Yang, X Xie, H Chen - Frontiers in Immunology, 2022 - frontiersin.org
Urinary tract infection (UTI) caused by uropathogens is the most common infectious disease
and significantly affects all aspects of the quality of life of the patients. However …

Molecular investigation of the direct anti-tumour effects of nonsteroidal anti-inflammatory drugs in a panel of canine cancer cell lines

R Yoshitake, K Saeki, M Watanabe, N Nakaoka… - The Veterinary …, 2017 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been suggested as effective adjunctive
anti-tumour agents in human and veterinary medicine. However, the molecular mechanisms …

The management of recurrent urinary tract infection: non-antibiotic bundle treatment

S Venturini, I Reffo, M Avolio, G Basaglia… - Probiotics and …, 2023 - Springer
Recurrent urinary tract infections (rUTIs) are a common condition with high morbidity and
negatively impact the quality of life. They account for approximately 25% of all antibiotic …