Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1–infected T cells
T Watanabe - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …
[HTML][HTML] HTLV-1 infection: An emerging risk. Pathogenesis, epidemiology, diagnosis and associated diseases
E Eusebio-Ponce, E Anguita… - Revista Española de …, 2019 - ncbi.nlm.nih.gov
ABSTRACT The Human T-Lymphotropic Virus type 1 (HTLV-1) affects up to 10 million
people worldwide. It is directly associated to one of the most aggressive T cell malignancies …
people worldwide. It is directly associated to one of the most aggressive T cell malignancies …
HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma
Human T cell leukemia virus type 1 (HTLV-1) mainly infects CD4+ T cells and induces
chronic, persistent infection in infected individuals, with some developing adult T cell …
chronic, persistent infection in infected individuals, with some developing adult T cell …
Human T cell leukemia virus type 1: persistence and pathogenesis
CRM Bangham - Annual review of immunology, 2018 - annualreviews.org
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …
More than just oncogenes: mechanisms of tumorigenesis by human viruses
Highlights•Viral infections cause approximately 12% of all human cancers.•Viral cancers
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …
HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment
N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …
Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence
G Ma, J Yasunaga, K Shimura… - Proceedings of the …, 2021 - National Acad Sciences
Human retroviruses, including human T cell leukemia virus type 1 (HTLV-1) and HIV type 1
(HIV-1), encode an antisense gene in the negative strand of the provirus. Besides coding for …
(HIV-1), encode an antisense gene in the negative strand of the provirus. Besides coding for …
Identification and characterization of a novel enhancer in the HTLV-1 proviral genome
M Matsuo, T Ueno, K Monde, K Sugata… - Nature …, 2022 - nature.com
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus with constantly active
antisense transcription from the proviral genome. Here, Matsuo et al. perform proviral DNA …
antisense transcription from the proviral genome. Here, Matsuo et al. perform proviral DNA …
Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis
Adult T-cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy caused
by human T-cell leukemia virus type-1 (HTLV-1). ATL is preceded by decades of chronic …
by human T-cell leukemia virus type-1 (HTLV-1). ATL is preceded by decades of chronic …