Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread

DO Pinto, S Al Sharif, G Mensah, M Cowen, P Khatkar… - Retrovirology, 2021 - Springer
Abstract Background The Human T-cell Lymphotropic Virus Type-1 (HTLV-1) is a blood-
borne pathogen and etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV …

Hypericin-photodynamic therapy inhibits the growth of adult T-cell leukemia cells through induction of apoptosis and suppression of viral transcription

L Xu, X Zhang, W Cheng, Y Wang, K Yi, Z Wang… - Retrovirology, 2019 - Springer
Background Adult T-cell leukemia (ATL) is an aggressive neoplasm caused by human T-cell
leukemia virus type 1 (HTLV-1). ATL carries a poor prognosis due to chemotherapy …

Role of virus-induced host cell epigenetic changes in cancer

V Pietropaolo, C Prezioso, U Moens - International Journal of Molecular …, 2021 - mdpi.com
The tumor viruses human T-lymphotropic virus 1 (HTLV-1), hepatitis C virus (HCV), Merkel
cell polyomavirus (MCPyV), high-risk human papillomaviruses (HR-HPVs), Epstein-Barr …

The past, present, and future of a human T-cell leukemia virus type 1 vaccine

JJ Tu, V Maksimova, L Ratner, AR Panfil - Frontiers in Microbiology, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus which
causes a lifelong infection. An estimated 5–10 million persons are infected with HTLV-1 …

[HTML][HTML] Gut eukaryotic virome in colorectal carcinogenesis: Is that a trigger?

L Massimino, S Lovisa, LA Lamparelli, S Danese… - Computational and …, 2021 - Elsevier
The human gut microbiota is composed of bacteria and viruses that might be associated with
colorectal cancer (CRC) onset and progression. Indeed, although viral infections have been …

Adult T-cell leukemia: a comprehensive overview on current and promising treatment modalities

R Hleihel, A Akkouche, H Skayneh, O Hermine… - Current Oncology …, 2021 - Springer
Abstract Purpose of the Review Adult T-cell leukemia (ATL) is an aggressive chemo-
resistant malignancy secondary to HTLV-1 retrovirus. Prognosis of ATL remains dismal …

Interplay between innate immunity and the viral oncoproteins Tax and HBZ in the pathogenesis and therapeutic response of HTLV-1 associated adult T cell leukemia

H El Hajj, A Bazarbachi - Frontiers in Immunology, 2022 - frontiersin.org
The Human T-cell Leukemia virus type 1 (HTLV-1) causes an array of pathologies, the most
aggressive of which is adult T-cell leukemia (ATL), a fatal blood malignancy with dismal …

NF-κB–induced R-loop accumulation and DNA damage select for nucleotide excision repair deficiencies in adult T cell leukemia

Y He, N Pasupala, H Zhi, B Dorjbal… - Proceedings of the …, 2021 - National Acad Sciences
Constitutive NF-κB activation (NF-κBCA) confers survival and proliferation advantages to
cancer cells and frequently occurs in T/B cell malignancies including adult T cell leukemia …

The roles of the virome in cancer

F Broecker, K Moelling - Microorganisms, 2021 - mdpi.com
Viral infections as well as changes in the composition of the intestinal microbiota and virome
have been linked to cancer. Moreover, the success of cancer immunotherapy with …

Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development

JI Yasunaga, M Matsuoka - Cancer science, 2018 - Wiley Online Library
Chronic infection is one of the major causes of cancer, and there are several mechanisms
for infectionmediated oncogenesis. Some pathogens encode gene products that behave …