Feedback loop regulation between pim kinases and tax keeps human T-cell leukemia virus type 1 viral replication in check

M Bellon, C Nicot - Journal of Virology, 2022 - Am Soc Microbiol
The Pim family of serine/threonine kinases promote tumorigenesis by enhancing cell
survival and inhibiting apoptosis. Three isoforms exist, Pim-1,-2, and-3, that are highly …

Immunopathogenesis and cellular interactions in human T-cell leukemia virus type 1 associated myelopathy/tropical spastic paraparesis

S Aghajanian, M Teymoori-Rad, G Molaverdi… - Frontiers in …, 2020 - frontiersin.org
HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) is a
neuropathological disorder in 1–3% of individuals infected with Human T-lymphotropic virus …

Stability of HTLV-2 antisense protein is controlled by PML nuclear bodies in a SUMO-dependent manner

L Dubuisson, F Lormières, S Fochi, J Turpin… - Oncogene, 2018 - nature.com
Since the identification of the antisense protein of HTLV-2 (APH-2) and the demonstration
that APH-2 mRNA is expressed in vivo in most HTLV-2 carriers, much effort has been …

Investigating the correlation between prominent viruses and hematological malignancies: a literature review

A Haghtalab, M Hejazi, N Goharnia, A Yekanlou… - Medical Oncology, 2024 - Springer
Extensive research has been conducted on the correlation between viral infections and
hematological cancers ever since the identification of the Rous Sarcoma Virus as a cancer …

[HTML][HTML] Mouse model recapitulates the phenotypic heterogeneity of human adult T-cell leukemia/lymphoma in bone

NA Kohart, SM Elshafae, W Supsahvad… - Journal of Bone …, 2019 - Elsevier
Adult T-cell leukemia/lymphoma has a unique relationship to bone including latency in the
marrow, and development of bone invasion, osteolytic tumors and humoral hypercalcemia of …

Cells of adult T-cell leukemia evade HTLV-1 Tax/NF-κB hyperactivation–induced senescence

AMD Shudofsky, CZ Giam - Blood advances, 2019 - ashpublications.org
Cells of adult T-cell leukemia evade HTLV-1 Tax/NF-κB hyperactivation–induced senescence |
Blood Advances | American Society of Hematology Skip to Main Content Advertisement …

A preclinical model for the atll lymphoma subtype with insights into the role of microenvironment in HTLV-1-mediated lymphomagenesis

M Vicario, A Mattiolo, B Montini, MA Piano… - Frontiers in …, 2018 - frontiersin.org
Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with
Human T cell Leukemia Virus type 1 (HTLV-1) infection. Among its four main clinical …

Mouse models that enhanced our understanding of adult T cell leukemia

S Moodad, A Akkouche, R Hleihel… - Frontiers in …, 2018 - frontiersin.org
Adult T cell Leukemia (ATL) is an aggressive lymphoproliferative malignancy secondary to
infection by the human T-cell leukemia virus type I (HTLV-I) and is associated with a dismal …

Non-structural proteins from human T-cell leukemia virus type 1 in cellular membranes—mechanisms for viral survivability and proliferation

ER Georgieva - International Journal of Molecular Sciences, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of illnesses, such as
adult T-cell leukemia/lymphoma, myelopathy/tropical spastic paraparesis (a …

and Biochemistry

RGYSB Liu, SLSZY Xu - Cell Physiol Biochem, 2014 - karger.com
Abstract Background/Aims: Long non-coding RNA (lncRNA) and glucagon-like peptide 1
receptor (GLP-1R) are crucial for heart development and for adult heart structural …