ROS‐mediated cancer cell killing through dietary phytochemicals

S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …

The role of antioxidant versus pro‐oxidant effects of green tea polyphenols in cancer prevention

SC Forester, JD Lambert - Molecular nutrition & food research, 2011 - Wiley Online Library
Consumption of green tea (Camellia sinensis) may provide protection against chronic
diseases, including cancer. Green tea polyphenols are believed to be responsible for this …

[HTML][HTML] New perspectives in iron chelation therapy for the treatment of neurodegenerative diseases

MT Nuñez, P Chana-Cuevas - Pharmaceuticals, 2018 - mdpi.com
Iron chelation has been introduced as a new therapeutic concept for the treatment of
neurodegenerative diseases with features of iron overload. At difference with iron chelators …

[HTML][HTML] Anticancer effects and molecular mechanisms of epigallocatechin-3-gallate

K Min, TK Kwon - Integrative medicine research, 2014 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG) is a type of catechin found in green tea. EGCG
exhibits a variety of activities, including anti-inflammatory, antidiabetes, antiobesity, and …

The anticancer properties of dietary polyphenols and its relation with apoptosis

P Fresco, F Borges, MPM Marques… - Current pharmaceutical …, 2010 - ingentaconnect.com
Aberrantly regulated apoptosis is involved in the pathogenesis of several diseases and
defective apoptosis leads to uncontrolled cell proliferation and tumorigenesis. Cancer is an …

[HTML][HTML] Structure-based classification and anti-cancer effects of plant metabolites

SA Shin, SY Moon, WY Kim, SM Paek, HH Park… - International journal of …, 2018 - mdpi.com
A variety of malignant cancers affect the global human population. Although a wide variety of
approaches to cancer treatment have been studied and used clinically (surgery …

[HTML][HTML] Natural polyphenols as modulators of etoposide anti-cancer activity

M Kluska, K Woźniak - International journal of molecular sciences, 2021 - mdpi.com
Polyphenols are naturally occurring compounds found in abundance in fruits and
vegetables. Their health-promoting properties and their use in the prevention and treatment …

[HTML][HTML] Pomegranate juice anthocyanidins induce cell death in human cancer cells by mobilizing intracellular copper ions and producing reactive oxygen species

M Farhan, A Rizvi, F Ali, A Ahmad, M Aatif… - Frontiers in …, 2022 - frontiersin.org
Anthocyanidins are the most abundant polyphenols in pomegranate juice. This class of
molecules includes Delphinidin (Del), Cyanidin (Cya), and Pelargonidin (Pel). Using …

A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols

H Yar Khan, H Zubair, M Fahad Ullah… - Current Drug …, 2012 - ingentaconnect.com
Plant-derived polyphenols, a prominent class of phytochemicals, are considered important
components of human diet. A number of them are known to possess chemopreventive and …

[HTML][HTML] The effects of green tea catechins in hematological malignancies

FI Della Via, MC Alvarez, RT Basting, STO Saad - Pharmaceuticals, 2023 - mdpi.com
Green tea catechins are bioactive polyphenol compounds which have attracted significant
attention for their diverse biological activities and potential health benefits. Notably …