Recent advancements in nanomaterial-mediated ferroptosis-induced cancer therapy: Importance of molecular dynamics and novel strategies

N Dhas, R Kudarha, R Tiwari, G Tiwari, N Garg… - Life Sciences, 2024 - Elsevier
Ferroptosis is a novel type of controlled cell death resulting from an imbalance between
oxidative harm and protective mechanisms, demonstrating significant potential in combating …

Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics

Z Ye, Y Bao, Z Chen, H Ye, Z Feng, Y Li, Y Zeng… - Coordination Chemistry …, 2024 - Elsevier
Cancer is an extremely significant disease that profoundly impacts human survival and
quality of life. Researchers have been searching for effective therapies, among which …

Au Nanorods Activated the Zn/Ce Composites with Cancer Cell Specific Cytotoxicity for Enhanced Chemodynamic Therapy

C Feng, W Zheng, Y Jiang, W Fu, W Huang, C Shen… - Nano Letters, 2023 - ACS Publications
Chemodynamic therapy based on the Fenton reaction has been developed as an extremely
promising modality for cancer therapeutics. In this study, a core–shell structure nanoplatform …

Progress and challenges in tumor ferroptosis treatment strategies: a comprehensive review of metal complexes and nanomedicine

Y Su, B Liu, B Wang, L Chan, C Xiong, L Lu, X Zhang… - Small, 2024 - Wiley Online Library
Ferroptosis is a new form of regulated cell death featuring iron‐dependent lipid peroxides
accumulation to kill tumor cells. A growing body of evidence has shown the potential of …

Membrane-anchoring clickable Iridium (III) nanosonosensitizer in situ evokes PANoptosis for augmented tumor sono-immunotherapy

X Xu, S Shabiti, X Zhang, J Zheng, N Liang, Z Wang… - Nano Today, 2024 - Elsevier
Developing activatable “off-on” sonosensitizers with superior sonodynamic activity and
immunogenic cell death (ICD) induction ability is urgently needed for precise and boosted …

A Highly Charged Positive Cage Causes Simultaneous Enhancement of Type‐II and O2‐Independent‐Type‐I Photodynamic Therapy via One‐/Two‐Photon …

XD Zhang, HJ Yu, SQ Guan, YL Lu, Y Zhang… - Small …, 2024 - Wiley Online Library
To solve the oxygen dependence problem of photodynamic therapy (PDT), it is critical to
explore photosensitizers that do not rely on O2 molecule to generate reactive oxygen …

Tumor-derived microvesicles for cancer therapy

S Yang, B Zheng, F Raza, S Zhang, W Yuan, J Su… - Biomaterials …, 2023 - pubs.rsc.org
Extracellular vesicles (EVs) are vesicles with lipid bilayer structures shed from the plasma
membrane of cells. Microvesicles (MVs) are a subset of EVs containing proteins, lipids …

Two-Photon Photodegradation of E3 Ubiquitin Ligase Cereblon by a Ru (II) Complex: Inducing Ferroptosis in Cisplatin-Resistant Tumor Cells

X Lin, M Zheng, K Xiong, F Wang, Y Chen… - Journal of Medicinal …, 2024 - ACS Publications
Using photodynamic therapy (PDT) to trigger nonconventional cell death pathways has
provided a new scheme for highly efficient and non-side effects to drug-resistant cancer …

Physical modulation of mesenchymal stem cell exosomes: A new perspective for regenerative medicine

D Wu, X Zhao, J Xie, R Yuan, Y Li, Q Yang… - Cell …, 2024 - Wiley Online Library
Mesenchymal stem cell‐derived exosomes (MSC‐Exo) offer promising therapeutic potential
for various refractory diseases, presenting a novel therapeutic strategy. However, their …

An iridium (iii)-based photosensitizer disrupting the mitochondrial respiratory chain induces ferritinophagy-mediated immunogenic cell death

T Feng, Z Tang, J Karges, J Shu, K Xiong, C Jin… - Chemical …, 2024 - pubs.rsc.org
Cancer cells have a strategically optimized metabolism and tumor microenvironment for
rapid proliferation and growth. Increasing research efforts have been focused on developing …