Arterial stiffness is a strong predictor of cardiovascular events and all-cause mortality in
middle-aged and old adults. Arterial stiffness has been limited to being an intermediate …

The pathological condition of insulin resistance prevents the neuroprotective effects of
insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Diabetes, hypertension, and dyslipidemia are obesity-related comorbidities that contribute to
the development of cardiovascular disease, one of the leading causes of death. In addition …

Cardiovascular diseases and type 2 diabetes mellitus (T2DM) have risen steadily
worldwide, particularly in low-income and developing countries. In the last hundred years …

Epithelial sodium channels (ENaC) are part of a complex network of interacting biochemical
pathways and as such are involved in several disease states. Dependent on site and type of …

Despite overwhelming epidemiological evidence, the contribution of hypertension (HTN) to
heart failure (HF) development has been undermined in current clinical practice. This is …

Abstract Background The triglyceride-glucose (TyG) index, a simple measure of insulin
resistance, is associated with intracranial atherosclerosis (ICAS) and stroke. In hypertensive …

A disorder of lipid metabolism is involved in cardiovascular diseases including hypertension.
A high level of small dense low-density lipoprotein cholesterol (sdLDL-C) is a strong risk …

Type 2 diabetes is often complicated with hypertension, such that 73.6% of patients≥ 18
years with type 2 diabetes also have hypertension. With increasing age, the risk of …