Treating COVID-19 with Medicinal Plants: Is It Even Conceivable? A Comprehensive Review

H Al-Jamal, S Idriss, R Roufayel, Z Abi Khattar… - Viruses, 2024 - mdpi.com
In 2020, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) challenged the
world with a global outbreak that led to millions of deaths worldwide. Coronavirus disease …

Novel chalcone derivatives of ursolic acid as acetylcholinesterase inhibitors: Synthesis, characterization, biological activity, ADME prediction, molecular docking and …

H Şenol, M Ghaffari-Moghaddam, GÖA Toraman… - Journal of Molecular …, 2024 - Elsevier
Acetylcholinesterase (AChE) is a critical target in the prevention of Alzheimer's Disease (AD)
progression. With the goal of developing potential acetylcholinesterase inhibitors, a new …

Cytotoxic meroterpenoids from brown alga Stypopodium schimperi (Kützing) Verlaque & Boudouresque with comprehensive molecular docking & dynamics and …

Ö Demirkıran, E Erol, H Şenol, İM Kesdi… - Process …, 2024 - Elsevier
In this study, five known meroterpenoids sargaol (1), flabellinone (2), stypodiol (3),
atomarianone A (4), atomarianone B (5), and a known steroid fucosterol (6) were isolated …

3‐Amino‐thiophene‐2‐carbohydrazide derivatives as anti Colon cancer Agents: synthesis, characterization, in‐Silico and in‐Vitro Biological activity studies

H Şenol, F Çakır - ChemistrySelect, 2023 - Wiley Online Library
In this study, starting from 3‐amino‐thiophene‐2‐carboxylic acid methyl ester, eighteen new
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …

Novel quinazoline–chromene hybrids as anticancer agents: Synthesis, biological activity, molecular docking, dynamics and ADME studies

FS Tokalı, H Şenol, Hİ Yetke… - Archiv der …, 2023 - Wiley Online Library
In this study, new quinazoline–chromene hybrid compounds were synthesized. The
cytotoxic effects on cell viability of the hybrid compounds were tested against A549 human …

Anthelminthic and antimicrobial effects of hedge woundwort (Stachys sylvatica L.) growing in Southern Kazakhstan

AZ Mukhamedsadykova, M Kasela… - Frontiers in …, 2024 - frontiersin.org
The Stachys L. genus has been widely used in traditional medicine in many countries
throughout the world. The study aimed to investigate the chemical composition and …

Exploring highly selective polymethoxy fenamate isosteres as novel anti-prostate cancer agents: Synthesis, biological activity, molecular docking, molecular dynamics …

FS Tokalı, H Şenol, Ş Ateşoğlu, P Tokalı… - Journal of Molecular …, 2025 - Elsevier
In this study, we synthesized and characterized sixteen new polymethoxy-substituted
hydrazone derivatives. These compounds were evaluated for their in vitro cytotoxic activity …

4‐Furfuryloxymethyl‐1, 2, 3‐triazol‐1‐yl‐acetohydrazide Hybrids as Cholinesterase and Carbonic Anhydrase Inhibitors: Synthesis, Characterization and …

H Şenol - ChemistrySelect, 2024 - Wiley Online Library
This study focused on the synthesis and evaluation of the biological activity of ten novel
acetohydrazide hybrid derivatives, having furfuryloxy‐1, 2, 3‐triazole ring. All the target …

Antioxidant properties and aldose reductase inhibitory potency of Viscum album L. extracts: experimental and computational insights

B Akyüz, B Şengül - Turkish Journal of Agriculture and …, 2024 - journals.tubitak.gov.tr
This study systematically investigates the antioxidant capacity and inhibitory impact of
Viscum album L. plant extracts on the aldose reductase (AR) enzyme through a combined …

Nipagin Türevi Yeni Hidrazonların Sentezi ve in Siliko Biyolojik Etkinliklerinin Belirlenmesi

H Şenol - Journal of the Institute of Science and Technology, 2023 - dergipark.org.tr
Bu çalışmada nipagin'den (metil paraben, metil-4-hidroksibenzoat) hareketle yeni seçici ve
düşük toksisiteye sahip potansiyel anti kanser ajanlar geliştirilmesi amacıyla arilidenhidrazid …