Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for …

Rapidly growing resistance of pathogenic bacteria to conventional antibiotics leads to
inefficiency of traditional approaches of countering infections and determines the urgent …

The mammalian gastrointestinal tract is home to a dense community of resident bacteria and
is also exposed to microorganisms from the external environment. The epithelial surface of …

Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …

Human body-surface epithelia coexist in close association with complex bacterial
communities and are protected by a variety of antibacterial proteins. C-type lectins of the …

As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Internuclear distances represent one of the main structural constraints in molecular structure
determination using solid-state NMR spectroscopy, complementing chemical shifts and …

The increasing prevalence of antibacterial resistance globally underscores the urgent need
to the update of antibiotics. Here, we describe a strategy for inducing the self-assembly of a …

Protein therapeutics carry inherent limitations of membrane impermeability and structural
instability, despite their predominant role in the modern pharmaceutical market. Effective …