In this review we describe the influence of modified nucleobases in order to understand the
changes they introduce in double and triple helix forming oligomers with the aim to study …

Per (trimethylsilyl)-2-N-acylguanine derivatives and tetra-O-acylpentofuranoses were
coupled [tin (IV) chloride or titanium (IV) chloride catalysis] to give predominant formation of …

In the last years DNA triplexes have been the subject of a very intense research effort, which
has been summarized in a vast number of books and reviews (see for example refs.[1-16]) …

Parallel-stranded hairpins with a polypyrimidine sequence linked to a complementary purine
carrying 8-aminopurines such as 8-aminoadenine, 8-aminoguanine and 8 …

Nucleic acid triplexes are formed when a DNA or RNA oligonucleotide binds to a polypurine‐
polypyrimidine‐rich sequence. Triplexes have wide therapeutic applications such as gene …

A DNA-triplex stabilizing purine (8-aminoguanine) is designed based on molecular
modeling and synthesized. The substitution of guanine by 8-aminoguanine largely stabilizes …

The structure of parallel-stranded duplexes of DNA-containing a mixture of guanines (G) and
adenines (A) is studied by means of molecular dynamics (MD) simulation, as well as NMR …

Abstract A nonnatural nucleoside, 7-(2-deoxy-β-D-erythro-pento-furanosyl)-guanine (d 7 G),
mimics protonated cytosine and specifically binds GC base pairs within a pyrimidine purine …

Abstract N7‐Alkyl‐substituted guanine (N7G) as a CH+ mimic has been introduced into
aminoethylglycyl PNA (aegPNA) forming a hairpin through a neutral linker derived from bis …

Oligonucleotides can interact in a very specific manner with homopurine–homopyrimidine
sequences of double-stranded DNA by forming triple helices (triplexes) that can be used to …