Modeling common and rare genetic risk factors of neuropsychiatric disorders in human induced pluripotent stem cells
AW Muhtaseb, J Duan - Schizophrenia research, 2022 - Elsevier
Recent genome-wide association studies (GWAS) and whole-exome sequencing of
neuropsychiatric disorders, especially schizophrenia, have identified a plethora of common …
neuropsychiatric disorders, especially schizophrenia, have identified a plethora of common …
Introduction to epigenetics in psychiatry
R Lee, D Avramopoulos - Epigenetics in psychiatry, 2014 - Elsevier
This introductory chapter provides a brief review of the current state of genetics research on
psychiatric disorders. It reports on the progress that has been accomplished in the last few …
psychiatric disorders. It reports on the progress that has been accomplished in the last few …
How variation in risk allele output and gene interactions shape the genetic architecture of schizophrenia
M Kasap, DS Dwyer - Genes, 2022 - mdpi.com
Schizophrenia is a highly heritable polygenic psychiatric disorder. Characterization of its
genetic architecture may lead to a better understanding of the overall burden of risk variants …
genetic architecture may lead to a better understanding of the overall burden of risk variants …
Inherited L1 retrotransposon insertions associated with risk for schizophrenia and bipolar disorder
BC Reiner, GA Doyle, AE Weller… - Schizophrenia …, 2021 - academic.oup.com
Studies of the genetic heritability of schizophrenia and bipolar disorder examining single
nucleotide polymorphisms (SNPs) and copy number variations have failed to explain a large …
nucleotide polymorphisms (SNPs) and copy number variations have failed to explain a large …