Supplementation of mitochondria from endometrial mesenchymal stem cells improves oocyte quality in aged mice

Q Zhang, JX Hao, BW Liu, YC Ouyang, JN Guo… - Cell …, 2023 - Wiley Online Library
Maternal ageing is one of the major causes of reduced ovarian reserve and low oocyte
quality in elderly women. Decreased oocyte quality is the main cause of age‐related …

Aging and oocyte competence: A molecular cell perspective

AF Ferreira, M Soares… - WIREs Mechanisms …, 2023 - Wiley Online Library
Follicular microenvironment is paramount in the acquisition of oocyte competence, which is
dependent on two interconnected and interdependent processes: nuclear and cytoplasmic …

Deletion of enzymes for de novo NAD+ biosynthesis accelerated ovarian aging

Q Yang, H Li, H Wang, W Chen, X Zeng, X Luo… - Aging …, 2023 - Wiley Online Library
Recent advances highlight the pivotal role of nicotinamide adenine dinucleotide (NAD+) in
ovarian aging. However, the roles of de novo NAD+ biosynthesis on ovarian aging are still …

[HTML][HTML] The significance of ovarian fibrosis

DA Landry, HT Vaishnav, BC Vanderhyden - Oncotarget, 2020 - ncbi.nlm.nih.gov
Ovarian aging is associated with significant changes in the structural organization of
collagen, resulting in ovarian fibrosis. In many other tissues, fibrosis increases risks …

Coenzyme Q10 stimulate reproductive vatality

X Nie, X Dong, Y Hu, F Xu, C Hu… - Drug design, development …, 2023 - Taylor & Francis
Female infertility and pregnancy maintenance are associate with various factors, including
quantity and quality of oocytes, genital inflammation, endometriosis, and other diseases …

C. elegans as a model organism to study female reproductive health

F Athar, NM Templeman - … Biochemistry and Physiology Part A: Molecular …, 2022 - Elsevier
Female reproductive health has been historically understudied and underfunded. Here, we
present the advantages of using a free-living nematode, Caenorhabditis elegans, as an …

Foetal exposure to the bisphenols BADGE and BPAF impairs meiosis through DNA oxidation in mouse ovaries

S Abdallah, A Jampy, D Moison, M Wieckowski… - Environmental …, 2023 - Elsevier
Many endocrine disruptors have been proven to impair the meiotic process which is
required for the production of healthy gametes. Bisphenol A is emblematic of such …

Melatonin restores the declining maturation quality and early embryonic development of oocytes in aged mice

J Qu, H Hu, H Niu, X Sun, Y Li - Theriogenology, 2023 - Elsevier
With increase in women's age, the reproductive capability of female mammals decreases
dramatically caused by age-related oxidative stress, coinciding with the decline in the …

Out of step societal and Darwinian adaptation during evolution is the cause of multiple women's health issues

Z Pei, W Lu, Y Feng, C Xu, AJW Hsueh - Human Reproduction, 2022 - academic.oup.com
During human evolution, major changes in our societal conditions and environment took
place without sufficient time for concomitant genetic alterations, leading to out of step …

Risk factors for different types of pregnancy losses: analysis of 15,210 pregnancies after embryo transfer

AM Yang, X Xu, Y Han, JJ Wei, GM Hao… - Frontiers in …, 2021 - frontiersin.org
Objective To evaluate the risk factors for different types of pregnancy losses after embryo
transfer (ET). Design Retrospective cohort study. Setting Reproductive medicine center …