For fully differentiated, long lived cells the maintenance of protein homeostasis
(proteostasis) becomes a crucial determinant of cellular function and viability. Neurons are …

Progesterone (P4) and glucocorticoid (GC) play crucial roles in the immunoregulation of a
mother to accept and maintain a semi-allogenic fetus. P4 concentration increases during …

DNA damage is a critical threat that poses significant challenges to all cells. To address this
issue, cells have evolved a sophisticated molecular and cellular process known as the DNA …

To evaluate the performance of expanded non-invasive prenatal testing (expanded
noninvasive prenatal testing, NIPT-Plus) in screening for fetal chromosomal abnormalities …

Advanced maternal age (AMA) is associated with reduced fertility due in part to diminished
ovarian follicle quantity, inferior oocyte quality, chromosome aneuploidy, and lower …

Oocyte aging directly affects the subsequent embryonic development. Epifriedelanol is the
active ingredient of Aster tataricus LF extract, and it possesses potential anti-cancer, anti …

Purpose To compare aneuploidy rates in early aborted tissues or blastocysts between in
vitro fertilization (IVF) cycles after the gonadotropin-releasing hormone (GnRH) antagonist …

Gametogenesis, the process of producing gametes, differs significantly between oocytes
and sperm. Most oocytes have chromosomal aneuploidies, indicating that chromosomal …

Human female fecundity decreases irreversibly as chronological age rises, adversely
affecting oocyte quality, consequently worsening pregnancy outcomes and increasing the …

Abstract Ethnopharmacological relevant Yangjing Zhongyu decoction (YJZYD) is a recipe
from a Chinese classic medical work and has been empirically used in female infertility for …