Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale
proteomics. In this review, we dissect the overall framework of the MS experiment into its key …

Mass spectrometry (MS)–based high-throughput proteomics is the core technique for large-
scale protein characterization. Due to the extreme complexity of proteomes, sophisticated …

Cyanobacteria are oxygen-evolving photoautotrophs with worldwide distribution in every
possible habitat, and they account for half of the global primary productivity. Because of their …

The study of the proteome (proteomics), which includes the dynamics of protein expression,
regulation, interactions and its function, has played a less prominent role in evolutionary and …

Owing to rapid growth in the elucidation of genome sequences of various organisms,
deducing proteome sequences has become imperative, in order to have an improved …

Biomarkers are pivotal for cancer detection, diagnosis, prognosis and therapeutic
monitoring. However, currently available cancer biomarkers have the disadvantage of …

Upon exposure to drought, plants undergo complex signal transduction events with
concomitant changes in the expression of genes, proteins and metabolites. For example …

Cancer is a heterogeneous multifactorial disease, which continues to be one of the main
causes of death worldwide. Despite the extensive efforts for establishing accurate diagnostic …

While several techniques are available in proteomics, LC-MS based analysis of complex
protein/peptide mixtures has turned out to be a mainstream analytical technique for …

Within the growing body of proteomics studies, issues addressing problems of ecotoxicology
are on the rise. Generally speaking, ecotoxicology uses quantitative expression changes of …