Emerging molecular biomarkers in osteoarthritis pathology

A Sandhu, JS Rockel, S Lively… - Therapeutic Advances …, 2023 - journals.sagepub.com
Osteoarthritis (OA) is the most common form of arthritis resulting in joint discomfort and
disability, culminating in decline in life quality. Attention has been drawn in recent years to …

Soluble biological markers in osteoarthritis

JC Rousseau, R Chapurlat… - Therapeutic Advances in …, 2021 - journals.sagepub.com
In recent years, markers research has focused on the structural components of cartilage
matrix. Specifically, a second generation of degradation markers has been developed …

[HTML][HTML] Terpenes as possible drugs for the mitigation of arthritic symptoms–a systematic review

AMS Carvalho, L Heimfarth, KA Santos, AG Guimarães… - Phytomedicine, 2019 - Elsevier
Background Arthritis is a syndrome associated with exacerbated inflammation, joint
destruction and chronic pain and disability. Chronic treatment of arthritis is associated with …

[HTML][HTML] TNF-α carried by plasma extracellular vesicles predicts knee osteoarthritis progression

X Zhang, MF Hsueh, JL Huebner, VB Kraus - Frontiers in Immunology, 2021 - frontiersin.org
Objectives To identify plasma extracellular vesicles (EVs) associated with radiographic knee
osteoarthritis (OA) progression. Methods EVs of small (SEV), medium (MEV) and large (LEV) …

[HTML][HTML] Towards precision medicine for osteoarthritis: focus on the synovial fluid proteome

L Moretti, D Bizzoca, A Geronimo, FL Moretti… - International Journal of …, 2022 - mdpi.com
Osteoarthritis (OA) is a joint degenerative disease that most affects old age. The study of
proteomics in synovial fluid (SF) has the task of providing additional elements to diagnose …

Recombinant protein drugs-based intra articular drug delivery systems for osteoarthritis therapy

H Huang, Y Lin, Y Jiang, Q Yao, R Chen… - European Journal of …, 2023 - Elsevier
Osteoarthritis (OA) is the most prevalent chronic degenerative joint disease. It weakens the
motor function of patients and imposes a significant economic burden on society. The …

The role of inflammation in mesenchymal stromal cell therapy in osteoarthritis, perspectives for post-traumatic osteoarthritis: a review

WF Theeuwes, MHJ van den Bosch… - …, 2021 - academic.oup.com
OA is a complex and highly prevalent degenerative disease affecting the whole joint, in
which factors like genetic predisposition, gender, age, obesity and traumas contribute to joint …

[HTML][HTML] Innate immunity at the core of sex differences in osteoarthritic pain?

N Valdrighi, JP Vago, AB Blom, FAJ Loo… - Frontiers in …, 2022 - frontiersin.org
Osteoarthritis (OA) is a progressive whole-joint disease; no disease-modifying drugs are
currently available to stop or slow its process. Symptoms alleviation is the only treatment …

[HTML][HTML] High prevalence of musculoskeletal pain in individuals with severe obesity: sites, intensity, and associated factors

CR Mendonça, M Noll… - The Korean Journal …, 2020 - synapse.koreamed.org
Background Musculoskeletal pain is associated with obesity; however, information on
factors associated with pain in adults with obesity and severe obesity is limited. The purpose …

[PDF][PDF] Pain management in rheumatology research, training, and practice

DG Borenstein, AL Hassett, D Pisetsky - Clin Exp Rheumatol, 2017 - clinexprheumatol.org
ABSTRACT The Pain Management Task Force of the American College of Rheumatology
published a report in 2010 highlighting pain management as a fundamental aspect of …