[HTML][HTML] Pathogenic Mechanisms and Therapeutic Approaches in Obesity-Related Knee Osteoarthritis

R Shumnalieva, G Kotov, P Ermencheva, S Monov - Biomedicines, 2023 - mdpi.com
The knee is the joint most frequently involved in osteoarthritis, a common joint disorder in the
adult population that is associated with significant chronic joint pain, reduced mobility and …

Combined detection of serum CTX‐II and C2C in a rat model of ACLT‐induced osteoarthritis

F Yu, H Bai, Z Zhang, TW Ma, L Gao - FEBS Open Bio, 2023 - Wiley Online Library
Osteoarthritis (OA) is a chronic degenerative bone and joint disease that often occurs in
aging animals. Currently, there are still no biomarkers that can effectively diagnose OA in the …

Elevated synovial fluid concentration of monocyte chemoattractant Protein-1 and Interleukin-8 in dogs with osteoarthritis of the stifle

SA Kleine, RM Gogal, C George… - Veterinary and …, 2020 - thieme-connect.com
Chemokines such as monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8)
have been shown to cause monocyte and natural killer cell chemotaxis and …

[HTML][HTML] The complexity of molecular processes in osteoarthritis of the knee joint

P Łęgosz, S Sarzyńska, Ł Pulik, D Kotrych… - Open Medicine, 2020 - degruyter.com
Osteoarthritis (OA) is a common medical problem leading to chronic pain and physical
disability among the world's population. Analyzing the molecular background of the …

[HTML][HTML] Concerted actions by PIICP, CTXII, and TNF-α in patients with juvenile idiopathic arthritis

K Winsz-Szczotka, K Kuźnik-Trocha, I Lachór-Motyka… - Biomolecules, 2021 - mdpi.com
Joint destruction in juvenile idiopathic arthritis (JIA), initiated in the early, preclinical stage of
the disease, is diagnosed on the basis of clinical evaluation and radiographic imaging. The …

骨关节炎疼痛的机制

秦夕茹, 张立智 - 中华全科医学, 2021 - zhqkyx.net
骨关节炎(osteoarthritis, OA) 是最常见的关节疾病, 其发病率逐年增加, 目前尚无有效的治愈方法
, 是导致老年人功能残疾的常见原因之一. 对膝OA 的认识不足, 预防及治疗延迟是导致其发病率 …

he utility of synovial fluid levels of ADAMTS9 and ADAMTS4 in predicting treatment responses to intraarticular steroid injections in patients with knee osteoarthritis

K Özler - Turkish Journal of Medical Sciences, 2020 - journals.tubitak.gov.tr
Background/aim: This study aims to identify the role of synovial fluid levels of a disintegrin
and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) and a disintegrin and …

Evaluation of the Regenerative Potential of Osteoarthritic Chondrocytes for Cartilage Tissue Engineering

C Davis - 2023 - deepblue.lib.umich.edu
Focal defects in articular cartilage and other traumatic joint injuries trigger destructive
pathways including inflammation, oxidative stress and increased expression of catabolic …

[HTML][HTML] Investigations of Pain and Extracellular Matrix Biomarkers for Improvement of Clinical Trail Endpoints and Design in Knee Osteoarthritis

AR Bihlet - 2022 - portal.findresearcher.sdu.dk
Background Osteoarthritis is the most prevalent arthritic disease affecting more than 500
million people in the world. Both the prevalence and incidence are expected to rise due to …

Relationships between Serum Interleukin-6, Radiographic Severity a WOMAC Index in Patients with Primary Knee Osteoarthritis

R Ahmed, N Soliman, S Elwan - The Egyptian Journal of …, 2023 - ejhm.journals.ekb.eg
Background: Osteoarthritis (OA) is the highest prevalent degenerative joint condition,
leading to joint discomfort and impaired function. Objective: This study aimed to examin the …