Amorphous solid dispersions (ASDs) are a proven system for achieving a supersaturated
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …

Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

Structural polymeric nanohybrids is presently a popular topic and can be conceived for
numerous functional applications, including the pH-sensitive oral colon-targeted drug …

The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates
much of the early drug development portfolio and poses a major challenge in …

This study reports the development of ritonavir-copovidone amorphous solid dispersions
(ASDs) and dosage forms thereof using selective laser sintering (SLS) 3-dimensional (3-D) …

This research demonstrates the influence of laser speed and the drug particle size on the
manufacturing of amorphous solid dispersions (ASD) and dosage forms thereof using …

This study aims to develop amorphous solid dispersion (ASD) of lumefantrine with a cost-
effective approach of spray anti-solvent precipitation. Four acidic polymers …

Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Specific mechanical energy (SME) is a frequently overlooked but essential parameter of hot-
melt extrusion (HME). It can determine whether an amorphous solid dispersion (ASD) can …

A successful candidate for oral drug delivery needs to possess adequate solubility and
dissolution rate to elicit its therapeutic action. Extensive research is being carried out to …