Understanding the mechanisms of migraine remains challenging as migraine is not a static
disorder, and even in its episodic form migraine remains an “evolutive” chronic condition …

Background Chronic pain conditions impose significant burdens worldwide.
Pharmacological treatments like opioids have limitations. Non-invasive non …

During the past decades, worldwide clinical and scientific interest in dry needling (DN)
therapy has grown exponentially. Various clinical effects have been credited to dry needling …

Background Figure 1 shows the pathways of nociceptive stimuli, including those conducting
pain, from the site of surgical injury passing through the peripheral nervous system to the …

Objective. To determine the prevalence and characteristics of fibromyalgia in the general
population. Methods. A random sample of 3,006 persons in Wichita, KS, were characterized …

Hyperalgesia and allodynia are frequent symptoms of disease and may be useful
adaptations to protect vulnerable tissues. Both may, however, also emerge as diseases in …

The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

Most patients who undergo surgery recover uneventfully and resume their normal daily
activities within weeks. Nevertheless, chronic postsurgical pain develops in an alarming …

Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a
very diverse audience needing content, with straight-forward, structured style of writing …

Until the 1960s, pain was considered an inevitable sensory response to tissue damage.
There was little room for the affective dimension of this ubiquitous experience, and none …