Drug therapy is essential when caring for elderly patients, but clearly it is a double-edged
sword. Elderly patients are at high risk of having drug interactions, but the prevalence of …

Nanomedicine seeks to manufacture drugs and other biologically relevant molecules that
are packaged into nanoscale systems for improved delivery. This includes known drugs …

Background Interaction of a drug or chemical with a biological system can result in a gene-
expression profile or signature characteristic of the event. Using a suitably robust algorithm …

Concise and authoritative, Clinical Toxicology: Principles and Mechanisms examines the
complex interactions associated with clinical toxicological events and chemical exposure or …

Many people have the mistaken notion that, being natural, all herbs and foods are safe; this
is not so. Very often, herbs and food may interact with medications you normally take, result …

Permeability-glycoprotein (P-gp) belongs to the ABS transporter protein family, with a high
expression rate in cancerous cells. The substrate/inhibitors of the protein are structurally …

Mycophenolic acid (MPA) is used as an immunosuppressant after organ transplantation and
for the treatment of immune diseases. There is increasing evidence that therapeutic drug …

In addition to the extrapulmonary disease manifestations and nonpulmonary organ system
dysfunction patterns that characterize specific forms of connective tissue disease (CTD) …

Introduction: Immunosuppressive drugs have a narrow therapeutic range and large inter-
individual response variability. This has prompted pharmacogenetic studies, mostly with …

BACKGROUND: Accurate functional assessment of patient immunosuppression after solid-
organ transplantation remains elusive. Despite therapeutic serum immunosuppressive drug …