Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …

Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
degeneration of the substantia nigra pars compacta and by accumulation of α-synuclein in …

Abstract Background and Purpose This update of the treatment guidelines was
commissioned by the European Academy of Neurology and the European section of the …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder
characterized by deficient synthesis of dopamine and serotonin. It presents in early infancy …

Objective To evaluate the effects of deep brain stimulation of the subthalamic nucleus (STN-
DBS) on motor complications in patients with Parkinson disease (PD) beyond 15 years after …

A robust body of evidence from randomized controlled trials has established the efficacy of
deep brain stimulation (DBS) in reducing off time and dyskinesias in levodopa‐treated …

The underlying cell types mediating predisposition to obesity remain largely obscure. Here,
we integrated recently published single-cell RNA-sequencing (scRNA-seq) data from 727 …

In implantable bioelectronics, which aim for semipermanent use of devices, biosafe energy
sources and packaging materials to protect devices are essential elements. However …