[HTML][HTML] How genomics can help biodiversity conservation

K Theissinger, C Fernandes, G Formenti, I Bista… - Trends in Genetics, 2023 - cell.com
The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

[HTML][HTML] The era of reference genomes in conservation genomics

G Formenti, K Theissinger, C Fernandes, I Bista… - Trends in ecology & …, 2022 - cell.com
Progress in genome sequencing now enables the large-scale generation of reference
genomes. Various international initiatives aim to generate reference genomes representing …

Genetic diversity loss in the Anthropocene

M Exposito-Alonso, TR Booker, L Czech, L Gillespie… - Science, 2022 - science.org
Anthropogenic habitat loss and climate change are reducing species' geographic ranges,
increasing extinction risk and losses of species' genetic diversity. Although preserving …

Chromosomal inversion polymorphisms shape the genomic landscape of deer mice

OS Harringmeyer, HE Hoekstra - Nature Ecology & Evolution, 2022 - nature.com
Chromosomal inversions are an important form of structural variation that can affect
recombination, chromosome structure and fitness. However, because inversions can be …

Leveraging base-pair mammalian constraint to understand genetic variation and human disease

PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li… - Science, 2023 - science.org
Thousands of genomic regions have been associated with heritable human diseases, but
attempts to elucidate biological mechanisms are impeded by an inability to discern which …

Genetics of adaptation

K Bomblies, CL Peichel - Proceedings of the National …, 2022 - National Acad Sciences
The rediscovery of Mendel's work showing that the heredity of phenotypes is controlled by
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …

Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution

KR Bredemeyer, LD Hillier, AJ Harris, GM Hughes… - Nature …, 2023 - nature.com
The role of structurally dynamic genomic regions in speciation is poorly understood due to
challenges inherent in diploid genome assembly. Here we reconstructed the evolutionary …

Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms

P Jay, M Chouteau, A Whibley, H Bastide… - Nature …, 2021 - nature.com
Chromosomal inversions are ubiquitous in genomes and often coordinate complex
phenotypes, such as the covariation of behavior and morphology in many birds, fishes …

Multi-omics pipeline and omics-integration approach to decipher plant's abiotic stress tolerance responses

R Roychowdhury, SP Das, A Gupta, P Parihar… - Genes, 2023 - mdpi.com
The present day's ongoing global warming and climate change adversely affect plants
through imposing environmental (abiotic) stresses and disease pressure. The major abiotic …

Coupling of barriers to gene exchange: causes and consequences

EB Dopman, KL Shaw, MR Servedio… - Cold Spring …, 2024 - cshperspectives.cshlp.org
Coupling has emerged as a concept to describe the transition from differentiated
populations to newly evolved species through the strengthening of reproductive isolation …