Development and in vitro effects of thiolated chitosan nanoparticles for the sustained delivery of inflammation suppressing bioactive peptide
Marine food derived compounds are highly studied as therapeutics due to their biological
activity. Moreover, due to high mucoadhesivity and solubility, chitosan (CS) is widely used …
activity. Moreover, due to high mucoadhesivity and solubility, chitosan (CS) is widely used …
TSG-6 (Tumor Necrosis Factor-α-Stimulated Gene/Protein-6): an emerging remedy for renal inflammation
Y Jiang, LM Glasstetter, A Lerman, LO Lerman - Hypertension, 2023 - Am Heart Assoc
The inflammatory response is a major pathological feature in most kidney diseases and
often evokes compensatory mechanisms. Recent evidence suggests that TSG-6 (tumor …
often evokes compensatory mechanisms. Recent evidence suggests that TSG-6 (tumor …
[HTML][HTML] Carrier-free curcumin nanoassemblies for enhancing therapy effects in inflammation related disease
L Zhang, H Xia, S Du, N Zhao, X Zhang, Q Pan, S Xu… - Materials & Design, 2022 - Elsevier
Hyperinflammation can lead to tissue injury, organ failure, and even fatalities by
overproducing proinflammatory cytokines. The long-term safety and outstanding anti …
overproducing proinflammatory cytokines. The long-term safety and outstanding anti …
[HTML][HTML] Synthesis of tetracyclic spirooxindolepyrrolidine-engrafted hydantoin scaffolds: crystallographic analysis, molecular docking studies and evaluation of their …
A Toumi, FIA Abdella, S Boudriga, TYA Alanazi… - Molecules, 2023 - mdpi.com
In a sustained search for novel potential drug candidates with multispectrum therapeutic
application, a series of novel spirooxindoles was designed and synthesized via …
application, a series of novel spirooxindoles was designed and synthesized via …
[HTML][HTML] Neuroprotective effects of meloxicam on transient brain ischemia in rats: the two faces of anti-inflammatory treatments
IF Ugidos, P González-Rodríguez… - Neural Regeneration …, 2023 - journals.lww.com
The inflammatory response plays an important role in neuroprotection and regeneration
after ischemic insult. The use of non-steroidal anti-inflammatory drugs has been a matter of …
after ischemic insult. The use of non-steroidal anti-inflammatory drugs has been a matter of …
[PDF][PDF] Tectochrysin Attenuates Cisplatin-induced Hepatotoxicity by Restoring Biochemical, Inflammatory and Histological Profile in Rats.
Cisplatin is an efficacious anticancerous chemotherapeutic agent that is used to cure
multiple types of malignancies. However, it has several hazardous effects on multiple …
multiple types of malignancies. However, it has several hazardous effects on multiple …
[HTML][HTML] Targeted therapy for head and neck squamous cell carcinoma microenvironment
Z Guo, K Li, P Liu, X Zhang, J Lv, X Zeng… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) originates from the squamous
epithelium of the oral cavity, oropharynx, larynx, and hypopharynx. HNSCC in the oral cavity …
epithelium of the oral cavity, oropharynx, larynx, and hypopharynx. HNSCC in the oral cavity …
Synthesis and biological evaluation of resveratrol amide derivatives as selective COX-2 inhibitors
M Xin, H Wu, Y Du, S Liu, F Zhao, X Mou - Chemico-Biological Interactions, 2023 - Elsevier
Selective COX-2 inhibitors have been considered to be reliable alternatives to tNSAIDs, but
most of them were withdrawn from the market due to their risk of heart attack and stroke …
most of them were withdrawn from the market due to their risk of heart attack and stroke …
[HTML][HTML] Unravelling the gastroprotective potential of Kefir: exploring antioxidant effects in preventing gastric ulcers
LZ Côco, R Aires, GR Carvalho, ES Belisário, MKK Yap… - Cells, 2023 - mdpi.com
The present study was conducted to evaluate the protective effect of milk kefir against NSAID-
induced gastric ulcers. Male Swiss mice were divided into three groups: control (Vehicle; …
induced gastric ulcers. Male Swiss mice were divided into three groups: control (Vehicle; …
Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study
Complications of the worldwide use of non-steroidal anti-inflammatory drugs (NSAIDs)
sparked scientists to design novel harmless alternatives as an urgent need. So, a unique …
sparked scientists to design novel harmless alternatives as an urgent need. So, a unique …