Fibroblast growth factor signaling in macrophage polarization: impact on health and diseases

L Shen, Y Li, H Zhao - Frontiers in Immunology, 2024 - frontiersin.org
Fibroblast growth factors (FGFs) are a versatile family of peptide growth factors that are
involved in various biological functions, including cell growth and differentiation, embryonic …

Inhibition of Immunoproteasome Attenuates NLRP3 Inflammasome Response by Regulating E3 Ubiquitin Ligase TRIM31

Y Lee, B Yoon, S Son, E Cho, KB Kim, EY Choi… - Cells, 2024 - mdpi.com
Excessive secretion of pro-inflammatory cytokines leads to the disruption of intestinal barrier
in inflammatory bowel disease (IBD). The inflammatory cytokine tumor necrosis factor alpha …

Selective autophagy of the immunoproteasomes suppresses innate inflammation

J Zhou, H Li, K Lu - Autophagy, 2024 - Taylor & Francis
Immunoproteasomes are involved in various inflammatory diseases. Upon stimulation,
standard constitutive proteasomes are partially replaced by newly formed …

Degrade to stay healthy—Proteolytic interplay during inflammation

C Münz - PLoS biology, 2024 - journals.plos.org
Proteasomes and autophagy constitute the 2 main proteolytic machineries for cytoplasmic
content. A new study in PLOS Biology now demonstrates that autophagy stimulation alters …