Activation of the miR-34a/SIRT1/p53 Signaling Pathway Contributes to the Progress of Liver Fibrosis via Inducing Apoptosis in Hepatocytes but Not in HSCs
XF Tian, FJ Ji, HL Zang, H Cao - PloS one, 2016 - journals.plos.org
Liver fibrosis results from a sustained wound healing response to chronic liver injury, and
the activation of nonparenchymal hepatic stellate cells (HSCs) is the pivotal process …
the activation of nonparenchymal hepatic stellate cells (HSCs) is the pivotal process …
MicroRNAs as promising biomarkers in cancer diagnostics
PJ Mishra - Biomarker research, 2014 - Springer
Cumulating data suggest that small noncoding-RNAs such as microRNAs (miRNAs) can be
utilized as potential biomarkers for the diagnosis and prognosis of a variety of diseases such …
utilized as potential biomarkers for the diagnosis and prognosis of a variety of diseases such …
[HTML][HTML] miR-223-5p suppresses tumor growth and metastasis in non-small cell lung cancer by targeting E2F8
L Dou, K Han, M Xiao, F Lv - Oncology research, 2019 - ncbi.nlm.nih.gov
Abstract miR-223-5p has been demonstrated to regulate the development and progression
of various cancers, such as hepatocellular carcinoma, breast cancer, and gastric carcinoma …
of various cancers, such as hepatocellular carcinoma, breast cancer, and gastric carcinoma …
[HTML][HTML] Development of novel miR-129 mimics with enhanced efficacy to eliminate chemoresistant colon cancer stem cells
N Wu, A Fesler, H Liu, J Ju - Oncotarget, 2017 - pmc.ncbi.nlm.nih.gov
Background Resistance to 5-Fluorouracil (5-FU) based chemotherapy is the major reason
for failure of treating patients with advanced colorectal cancer. Materials and methods In this …
for failure of treating patients with advanced colorectal cancer. Materials and methods In this …
[Retracted] miR‐223‐5p Suppresses OTX1 to Mediate Malignant Progression of Lung Squamous Cell Carcinoma Cells
Y Lu - Computational and Mathematical Methods in Medicine, 2021 - Wiley Online Library
Background. Lung squamous cell carcinoma (LUSC) features high morbidity and mortality
as a worldwide malignant tumor. This study mainly explored a miR‐223‐5p‐dependent …
as a worldwide malignant tumor. This study mainly explored a miR‐223‐5p‐dependent …
[HTML][HTML] The expanding regulatory universe of p53 in gastrointestinal cancer
A Fesler, N Zhang, J Ju - F1000Research, 2016 - ncbi.nlm.nih.gov
Tumor suppresser gene TP53 is one of the most frequently deleted or mutated genes in
gastrointestinal cancers. As a transcription factor, p53 regulates a number of important …
gastrointestinal cancers. As a transcription factor, p53 regulates a number of important …
Improving classification of mature microRNA by solving class imbalance problem
Y Wang, X Li, B Tao - Scientific reports, 2016 - nature.com
Abstract MicroRNAs (miRNAs) are~ 20–25 nucleotides non-coding RNAs, which regulated
gene expression in the post-transcriptional level. The accurate rate of identifying the start sit …
gene expression in the post-transcriptional level. The accurate rate of identifying the start sit …
[PDF][PDF] Correlation between miR-19a inhibition and radiosensitivity in SiHa cervical cancer cells
Y Wang, Y Wang, W Zhong, K Gulina - J BUON, 2017 - jbuon.com
Purpose: MicroRNAs (miRs) have been implicated in many aspects of tumor cell
development and survival, including sensitivity to radiotherapy. In particular, miR-19a …
development and survival, including sensitivity to radiotherapy. In particular, miR-19a …
Steady-state kinetics and spectroscopic characterization of enzyme–tRNA interactions for the non-heme diiron tRNA-monooxygenase, MiaE
BP Subedi, AL Corder, S Zhang, FW Foss Jr… - Biochemistry, 2015 - ACS Publications
MiaE [2-methylthio-N 6-isopentenyl-adenosine (37)-tRNA monooxygenase] isolated from
Salmonella typhimurium is a unique non-heme diiron enzyme that catalyzes the O2 …
Salmonella typhimurium is a unique non-heme diiron enzyme that catalyzes the O2 …