Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …

Highly bioavailable forms of curcumin and promising avenues for curcumin-based research and application: a review

SJ Stohs, O Chen, SD Ray, J Ji, LR Bucci, HG Preuss - Molecules, 2020 - mdpi.com
Curcumin exerts a wide range of beneficial physiological and pharmacological activities,
including antioxidant, anti-amyloid, anti-inflammatory, anti-microbial, anti-neoplastic …

Curcumin improves intestinal barrier function: modulation of intracellular signaling, and organization of tight junctions

J Wang, SS Ghosh, S Ghosh - American Journal of …, 2017 - journals.physiology.org
Association between circulating lipopolysaccharide (LPS) and metabolic diseases (such as
type 2 diabetes and atherosclerosis) has shifted the focus from high-fat high-cholesterol …

A novel highly bioavailable curcumin formulation improves symptoms and diagnostic indicators in rheumatoid arthritis patients: a randomized, double-blind, placebo …

A Amalraj, K Varma, J Jacob, C Divya… - Journal of medicinal …, 2017 - liebertpub.com
Rheumatoid arthritis (RA) is an autoimmune, chronic systemic inflammatory disorder. The
long-term use of currently available drugs for the treatment of RA has many potential side …

Effects of curcumin consumption on human chronic diseases: A narrative review of the most recent clinical data

M Mantzorou, E Pavlidou, G Vasios… - Phytotherapy …, 2018 - Wiley Online Library
Numerous clinical trials have investigated the potential beneficial effects of curcumin
supplementation against several human chronic diseases. Up to now, it has been claimed …

Toxic tau oligomers modulated by novel curcumin derivatives

F Lo Cascio, N Puangmalai, A Ellsworth, F Bucchieri… - Scientific reports, 2019 - nature.com
The pathological aggregation and accumulation of tau, a microtubule-associated protein, is
a common feature amongst more than 18 different neurodegenerative diseases that are …

Comparative oral absorption of curcumin in a natural turmeric matrix with two other curcumin formulations: An open‐label parallel‐arm study

S Gopi, J Jacob, K Varma, S Jude… - Phytotherapy …, 2017 - Wiley Online Library
Curcuminoids are the major bioactive molecules in turmeric, and poor bioavailability deters
them from being the major components of many health and wellness applications. This study …

[HTML][HTML] Turmeric: potential health benefits

K Singletary - Nutrition Today, 2020 - journals.lww.com
For centuries, Curcuma longa (turmeric) was used as a spice in Asian cuisine and as a
medicinal herb for treatment of inflammation, pain, wound healing, and digestive disorders …

Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin

D Shan, J Wang, Q Di, Q Jiang, Q Xu - Food & Function, 2022 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) has increasingly become a serious public health
problem. There is growing evidence that nonylphenol (NP) exposure may cause steatosis …

Effects of curcumin and its different formulations in preclinical and clinical studies of peripheral neuropathic and postoperative pain: a comprehensive review

P Basu, C Maier, A Basu - International Journal of Molecular Sciences, 2021 - mdpi.com
Lesion or disease of the somatosensory system leads to the development of neuropathic
pain. Peripheral neuropathic pain encompasses damage or injury of the peripheral nervous …