Efficient inflammation resolution is important not only for the termination of the inflammatory
response but also for the restoration of tissue integrity. An integral process to resolution of …

Neutrophils (also named polymorphonuclear leukocytes or PMN) are essential components
of the immune system, rapidly recruited to sites of inflammation, providing the first line of …

Macrophages acquire anti-inflammatory and proresolving functions to facilitate resolution of
inflammation and promote tissue repair. While alternatively activated macrophages (AAMs) …

Inflammation resolution is an active process that functions to restore tissue homeostasis. The
participation of the plasminogen (Plg)/plasmin (Pla) system in the productive phase of …

From development to aging and disease, the brain parenchyma is under the constant threat
of debris accumulation, in the form of dead cells and protein aggregates. To prevent …

Inflammation resolution is an active process that functions to restore tissue homeostasis.
Clearance of apoptotic leukocytes by efferocytosis at inflammatory sites plays an important …

Although anti-inflammatory drugs are among the most common class of marketed drugs,
chronic inflammatory conditions such as rheumatoid arthritis, multiple sclerosis or …

Respiratory diseases include a wide range of pathologies with different clinical
manifestations, affecting the normal airways and lung function. An increase in the …

Glucocorticoid (GC)-induced leucine zipper (GILZ) has been shown to mediate or mimic
several actions of GC. This study assessed the role of GILZ in self-resolving and GC-induced …

The ATP-binding cassette (ABC) transporters play a key role in drug pharmacokinetics.
These membrane transporters expressed within physiological barriers can be a source of …