A computational approach to identify blood cell-expressed Parkinson's disease biomarkers that are coordinately expressed in brain tissue

MA Moni, HK Rana, MB Islam, MB Ahmed, H Xu… - Computers in biology …, 2019 - Elsevier
Identification of genes whose regulation of expression is functionally similar in both brain
tissue and blood cells could in principle enable monitoring of significant neurological traits …

Repositioning of hypoglycemic drug linagliptin for cancer treatment

Y Li, Y Li, D Li, K Li, Z Quan, Z Wang… - Frontiers in …, 2020 - frontiersin.org
Background Drug repositioning, development of new uses for marketed drugs, is an effective
way to discover new antitumor compounds. In this study, we used a new method, filtering …

Identification and characterization of the structure–activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum …

Q Wang, Y Wang, Y Li, B Wen, Z Dai, S Ma, Y Zhang - Scientific reports, 2017 - nature.com
The adverse effects of Polygonum (P.) multiflorum, including abnormal bilirubin metabolism,
are a serious public health issue. As uridine diphosphate (UDP)-glucuronosyltransferase …