Mitochondrial dysfunction: roles in skeletal muscle atrophy
X Chen, Y Ji, R Liu, X Zhu, K Wang, X Yang… - Journal of Translational …, 2023 - Springer
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle
health, and damage to mitochondria can lead to a series of pathophysiological changes …
health, and damage to mitochondria can lead to a series of pathophysiological changes …
Physiological and environmental factors affecting cancer risk and prognosis in obesity
PFS Etet, L Vecchio, AHN Kamdje, PN Mimche… - Seminars in Cancer …, 2023 - Elsevier
Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …
imbalance between energy intake and expenditure. Available epidemiological and clinical …
Ketogenic diets in pancreatic cancer and associated cachexia: cellular mechanisms and clinical perspectives
NE Cortez, GG Mackenzie - Nutrients, 2021 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and extremely therapy-resistant
cancer. It is estimated that up to 80% of PDAC patients present with cachexia, a multifactorial …
cancer. It is estimated that up to 80% of PDAC patients present with cachexia, a multifactorial …
Malnutrition, sarcopenia, and cancer cachexia in gynecologic cancer
M Morton, J Patterson, J Sciuva, J Perni, F Backes… - Gynecologic …, 2023 - Elsevier
Patients with gynecologic cancers are at risk for malnutrition, cancer cachexia, and
sarcopenia. Accumulating data supports that malnourished patients with gynecologic cancer …
sarcopenia. Accumulating data supports that malnourished patients with gynecologic cancer …
Molecular mechanisms and current treatment options for cancer cachexia
Simple Summary The primary characteristics of cancer cachexia are weakness, weight loss,
atrophy, fat reduction, and systemic inflammation. Cachexia is strongly associated with …
atrophy, fat reduction, and systemic inflammation. Cachexia is strongly associated with …
Targeting cancer cachexia: Molecular mechanisms and clinical study
Cancer cachexia is a complex systemic catabolism syndrome characterized by muscle
wasting. It affects multiple distant organs and their crosstalk with cancer constitute cancer …
wasting. It affects multiple distant organs and their crosstalk with cancer constitute cancer …
Psoas muscle index as a predictor of perioperative outcomes in geriatric patients undergoing spine surgery
Study Design Single-center retrospective study. Objective The objective of this study was to
evaluate the association of psoas muscle mass defined sarcopenia with perioperative …
evaluate the association of psoas muscle mass defined sarcopenia with perioperative …
[HTML][HTML] Molecular mechanisms of cancer cachexia. Role of exercise training
E Tamayo-Torres, A Garrido, R de Cabo… - Molecular Aspects of …, 2024 - Elsevier
Cancer-associated cachexia represents a multifactorial syndrome mainly characterized by
muscle mass loss, which causes both a decrease in quality of life and anti-cancer therapy …
muscle mass loss, which causes both a decrease in quality of life and anti-cancer therapy …
Targeting Epigenetic Regulators with HDAC and BET Inhibitors to Modulate Muscle Wasting
L Nevi, N Pöllänen, F Penna, G Caretti - International Journal of …, 2023 - mdpi.com
Epigenetic changes contribute to the profound alteration in the transcriptional program
associated with the onset and progression of muscle wasting in several pathological …
associated with the onset and progression of muscle wasting in several pathological …
The incidence and management of cancer-related anorexia during treatment with vascular endothelial growth factor receptor-tyrosine kinase inhibitors
S Takahashi, K Matsumoto, K Ohba… - Cancer Management …, 2023 - Taylor & Francis
Cancer-related anorexia is a common complication and frequently occurs in cancer patients
treated with vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR …
treated with vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR …