Scalemic natural products
S Mazzotta, V Rositano, L Senaldi, A Bernardi… - Natural Product …, 2023 - pubs.rsc.org
Covering: up to the end of 2022The area of scalemic natural products is often enigmatic from
a mechanistic standpoint, since low optical purity is observed in compounds having multiple …
a mechanistic standpoint, since low optical purity is observed in compounds having multiple …
Development of a new LC-MS method for accurate and sensitive determination of 33 pyrrolizidine and 21 tropane alkaloids in plant-based food matrices
Z Dzuman, P Jonatova… - Analytical and …, 2020 - Springer
Abstract Setting of maximum limits for a number of plant alkaloids is under discussion in the
EU. The novel method developed and optimized in this study enables simultaneous …
EU. The novel method developed and optimized in this study enables simultaneous …
Cobalt-Catalyzed Enantioselective Hydroboration of α-Substituted Acrylates
Even though metal-catalyzed enantioselective hydroborations of alkenes have attracted
enormous attention, few preparatively useful reactions of α-alkyl acrylic acid derivatives are …
enormous attention, few preparatively useful reactions of α-alkyl acrylic acid derivatives are …
The role of long‐distance mobile metabolites in the plant stress response and signaling
J Cai, D Li, A Aharoni - The Plant Journal, 2023 - Wiley Online Library
Plants developed sophisticated mechanisms to perceive environmental stimuli and generate
appropriate signals to maintain optimal growth and stress responses. A fascinating strategy …
appropriate signals to maintain optimal growth and stress responses. A fascinating strategy …
Deep in the bowel: highly interpretable neural encoder-decoder networks predict gut metabolites from gut microbiome
Background Technological advances in next-generation sequencing (NGS) and
chromatographic assays [eg, liquid chromatography mass spectrometry (LC-MS)] have …
chromatographic assays [eg, liquid chromatography mass spectrometry (LC-MS)] have …
Tropinone reductase: A comprehensive review on its role as the key enzyme in tropane alkaloids biosynthesis
X Hu, W Liu, Y Yan, H Deng, Y Cai - International Journal of Biological …, 2023 - Elsevier
TAs, including hyoscyamine and scopolamine, were used to treat neuromuscular disorders
ranging from nerve agent poisoning to Parkinson's disease. Tropinone reductase I (TR-I; EC …
ranging from nerve agent poisoning to Parkinson's disease. Tropinone reductase I (TR-I; EC …
Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
Y Zhou, J Xu, HJ MacIsaac, RM McKay, R Xu… - Frontiers in …, 2023 - frontiersin.org
Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa
threaten the ecological integrity and beneficial uses of lakes globally. In addition to …
threaten the ecological integrity and beneficial uses of lakes globally. In addition to …
Review of traditional uses, phytochemistry and pharmacology of Tibetan Medicine tangchong
T Wang, Q Li, Z Zhou, J Liu, Y Tao, Y Zhang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Tangchong (ཐང་ ཕྲོམ།), a term in the Tibetan
language, encompasses a diverse group of plants belonging to different genera of the …
language, encompasses a diverse group of plants belonging to different genera of the …
Biochemical and metabolic insights into hyoscyamine dehydrogenase
F Qiu, Y Yan, J Zeng, JP Huang, L Zeng, W Zhong… - ACS …, 2021 - ACS Publications
Hyoscyamine, a member of the class of compounds known as tropane alkaloids (TAs), is
clinically used as an anticholinergic drug. Previous research has predicted that …
clinically used as an anticholinergic drug. Previous research has predicted that …