Transcriptomic analysis of genes related to alkaloid biosynthesis and the regulation mechanism under precursor and methyl jasmonate treatment in Dendrobium …

C Jiao, M Wei, H Fan, C Song, Z Wang… - Frontiers in Plant …, 2022 - frontiersin.org
Dendrobium officinale is both a traditional herbal medicine and a plant of high ornamental
and medicinal value. Alkaloids, especially terpenoid indole alkaloids (TIAs), with …

Metabolic Effects of Elicitors on the Biosynthesis of Tropane Alkaloids in Medicinal Plants

Y Wen, Y Liao, Y Tang, H Zhang, J Zhang, Z Liao - Plants, 2023 - mdpi.com
Tropane alkaloids (TAs) are large secondary metabolite alkaloids that find extensive
applications in the synthesis of antidotes, anesthetics, antiemetics, motion sickness drugs …

Plant alkaloids: production, extraction, and potential therapeutic properties

AG Pereira, L Cassani, P Garcia-Oliveira… - … : From Nature, Through …, 2023 - Springer
Alkaloids are a type of secondary metabolites that can be found in different parts of plants.
This group of compounds is diverse and can be divided into nine subgroups: pyridine …

[HTML][HTML] Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity …

K Piechowska, M Świtalska, J Cytarska… - European journal of …, 2019 - Elsevier
We have designed novel tropinone-thiazole derivatives that showed high antiproliferative
activity against a variety of cancer cell lines via caspase 3/7 activation mechanism. Among …

Compartmentalization at the interface of primary and alkaloid metabolism

JL Watkins, PJ Facchini - Current Opinion in Plant Biology, 2022 - Elsevier
Plants produce many compounds used by humans as medicines, including alkaloids of the
benzylisoquinoline (BIA), monoterpene indole (MIA) and tropane classes. The biosynthetic …

Moringa oleifera Nanoparticles Demonstrate Antifungal Activity Against Plant Pathogenic Fungi

A Jenish, S Ranjani, S Hemalatha - Applied biochemistry and …, 2022 - Springer
Fungal diseases in plants are creating numerous problems in the developed and
developing nations. Silver, a notable metal because of its inertness and its role in …

Multiple independent losses of the biosynthetic pathway for two tropane alkaloids in the Solanaceae family

J Yang, Y Wu, P Zhang, J Ma, YJ Yao, YL Ma… - Nature …, 2023 - nature.com
Hyoscyamine and scopolamine (HS), two valuable tropane alkaloids of significant medicinal
importance, are found in multiple distantly related lineages within the Solanaceae family …

Plant copper metalloenzymes as prospects for new metabolism involving aromatic compounds

LS Mydy, DN Chigumba, RD Kersten - Frontiers in Plant Science, 2021 - frontiersin.org
Copper is an important transition metal cofactor in plant metabolism, which enables diverse
biocatalysis in aerobic environments. Multiple classes of plant metalloenzymes evolved and …

Determination of scopolamine and butylscopolamine in beverages, urine and Buscopan® tablets samples using electrophoresis microchip with integrated contactless …

HI Santos, KMP Pinheiro, EM Richter, WKT Coltro - Talanta, 2024 - Elsevier
The number of cases in which scopolamine (SCO) was used for both recreational and
predatory purposes has increased dramatically in recent decades. Linked to this, there is a …

Highly stereoselective construction of polycyclic benzofused tropane scaffolds and their latent bioactivities: Bifunctional phosphonium salt-enabled …

JP Tan, X Li, Y Chen, X Rong, L Zhu, C Jiang… - Science China …, 2020 - Springer
Structurally fused heterocycles encompassing a centerpiece of benzotropane are significant
scaffolds with a plethora of promising biological activities, but such molecular architectures …