The patent review of the biological activity of tropane containing compounds

TA Farghaly, GS Masaret… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Tropane-derived medications have historically played a substantial role in
pharmacotherapy. Both natural and synthetic derivatives of tropane find application in …

[HTML][HTML] Synthesis and antimalarial activity of 1, 4-disubstituted piperidine derivatives

R Seck, A Gassama, S Cojean, C Cavé - Molecules, 2020 - mdpi.com
In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and
with a less side-effects, we have designed and synthesized a library of 1, 4-disubstituted …

[HTML][HTML] Geographically associated endophytic fungi contribute to the tropane alkaloids accumulation of Anisodus tanguticus

B Wang, C Chen, Y Xiao, Y He, Y Gao… - Frontiers in Plant …, 2023 - frontiersin.org
Anisodus tanguticus is a valuable plant for extracting tropane alkaloids. However, the
mechanisms by which plant microbiome mediate the accumulation of tropane alkaloids in …

Scopolamine and atropine in feeds–determination with liquid chromatography mass spectrometry

E Kowalczyk, K Kwiatek - Food Additives & Contaminants: Part A, 2022 - Taylor & Francis
Tropane alkaloids (TAs) are naturally occurring plant toxins. Due to the fact that TA-
producing plants can enter the food chain, they pose a risk for animals and human health …

Alkaloids and terpenoids: synthesis, classification, isolation and purification, reactions, and applications

MM Phukan, SR Sangma, D Kalita, P Bora… - Handbook of …, 2023 - Elsevier
In the past few decades there has been a tremendous spike in studies pertaining to
secondary metabolite research specifically with regard to their prominence as a source of …

Dualplex lateral flow assay for simultaneous scopolamine and “cannibal drug” detection based on receptor-gated mesoporous nanoparticles

E Garrido, E Climent, MD Marcos, F Sancenón… - Nanoscale, 2022 - pubs.rsc.org
We report herein the design of a strip-based rapid test utilizing bio-inspired hybrid
nanomaterials for the in situ and at site detection of the drug scopolamine (SCP) using a …

[HTML][HTML] Metabolomic and transcriptomic analyses identify external conditions and key genes underlying high levels of toxic glycoalkaloids in tubers of stress-sensitive …

I Merino, AO Guasca, A Krmela, U Arif, A Ali… - Frontiers in Plant …, 2023 - frontiersin.org
Introduction High levels of toxic steroidal glycoalkaloids (SGAs) in potato tubers constitute a
recognized food quality problem. Tuber SGA levels vary between potato cultivars and can …

A novel bHLH gene responsive to low nitrogen positively regulates the biosynthesis of medicinal tropane alkaloids in Atropa belladonna

Y Gou, Y Jing, J Song, MM Nagdy, C Peng… - International Journal of …, 2024 - Elsevier
Medicinal tropane alkaloids (TAs), including hyoscyamine, anisodamine and scopolamine,
are essential anticholinergic drugs specifically produced in several solanaceous plants …

Effect of culture time on secondary metabolite production from MeJA-stimulated in vitro roots of Hyoscyamus niger L.

H Deveci, T Demirci, NG Baydar - International Journal of …, 2022 - dergipark.org.tr
This study was conducted to determine the effects of different culture times on root growth
and accumulation of secondary metabolites in adventitious roots from Hyoscyamus niger …

The chromosome-scale genome and the genetic resistance machinery against insect herbivores of the Mexican toloache, Datura stramonium

IM De-la-Cruz, K Oyama… - G3: Genes, Genomes …, 2024 - academic.oup.com
Plant resistance refers to the heritable ability of plants to reduce damage caused by natural
enemies, such as herbivores and pathogens, either through constitutive or induced traits like …