The patent review of the biological activity of tropane containing compounds
TA Farghaly, GS Masaret… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Tropane-derived medications have historically played a substantial role in
pharmacotherapy. Both natural and synthetic derivatives of tropane find application in …
pharmacotherapy. Both natural and synthetic derivatives of tropane find application in …
[HTML][HTML] Synthesis and antimalarial activity of 1, 4-disubstituted piperidine derivatives
In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and
with a less side-effects, we have designed and synthesized a library of 1, 4-disubstituted …
with a less side-effects, we have designed and synthesized a library of 1, 4-disubstituted …
[HTML][HTML] Geographically associated endophytic fungi contribute to the tropane alkaloids accumulation of Anisodus tanguticus
B Wang, C Chen, Y Xiao, Y He, Y Gao… - Frontiers in Plant …, 2023 - frontiersin.org
Anisodus tanguticus is a valuable plant for extracting tropane alkaloids. However, the
mechanisms by which plant microbiome mediate the accumulation of tropane alkaloids in …
mechanisms by which plant microbiome mediate the accumulation of tropane alkaloids in …
Scopolamine and atropine in feeds–determination with liquid chromatography mass spectrometry
E Kowalczyk, K Kwiatek - Food Additives & Contaminants: Part A, 2022 - Taylor & Francis
Tropane alkaloids (TAs) are naturally occurring plant toxins. Due to the fact that TA-
producing plants can enter the food chain, they pose a risk for animals and human health …
producing plants can enter the food chain, they pose a risk for animals and human health …
Alkaloids and terpenoids: synthesis, classification, isolation and purification, reactions, and applications
In the past few decades there has been a tremendous spike in studies pertaining to
secondary metabolite research specifically with regard to their prominence as a source of …
secondary metabolite research specifically with regard to their prominence as a source of …
Dualplex lateral flow assay for simultaneous scopolamine and “cannibal drug” detection based on receptor-gated mesoporous nanoparticles
E Garrido, E Climent, MD Marcos, F Sancenón… - Nanoscale, 2022 - pubs.rsc.org
We report herein the design of a strip-based rapid test utilizing bio-inspired hybrid
nanomaterials for the in situ and at site detection of the drug scopolamine (SCP) using a …
nanomaterials for the in situ and at site detection of the drug scopolamine (SCP) using a …
[HTML][HTML] Metabolomic and transcriptomic analyses identify external conditions and key genes underlying high levels of toxic glycoalkaloids in tubers of stress-sensitive …
Introduction High levels of toxic steroidal glycoalkaloids (SGAs) in potato tubers constitute a
recognized food quality problem. Tuber SGA levels vary between potato cultivars and can …
recognized food quality problem. Tuber SGA levels vary between potato cultivars and can …
A novel bHLH gene responsive to low nitrogen positively regulates the biosynthesis of medicinal tropane alkaloids in Atropa belladonna
Y Gou, Y Jing, J Song, MM Nagdy, C Peng… - International Journal of …, 2024 - Elsevier
Medicinal tropane alkaloids (TAs), including hyoscyamine, anisodamine and scopolamine,
are essential anticholinergic drugs specifically produced in several solanaceous plants …
are essential anticholinergic drugs specifically produced in several solanaceous plants …
Effect of culture time on secondary metabolite production from MeJA-stimulated in vitro roots of Hyoscyamus niger L.
This study was conducted to determine the effects of different culture times on root growth
and accumulation of secondary metabolites in adventitious roots from Hyoscyamus niger …
and accumulation of secondary metabolites in adventitious roots from Hyoscyamus niger …
The chromosome-scale genome and the genetic resistance machinery against insect herbivores of the Mexican toloache, Datura stramonium
IM De-la-Cruz, K Oyama… - G3: Genes, Genomes …, 2024 - academic.oup.com
Plant resistance refers to the heritable ability of plants to reduce damage caused by natural
enemies, such as herbivores and pathogens, either through constitutive or induced traits like …
enemies, such as herbivores and pathogens, either through constitutive or induced traits like …